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dc.contributor.authorHaapala, Eero A.
dc.contributor.authorVäistö, Juuso
dc.contributor.authorIhalainen, Johanna K.
dc.contributor.authorTomaselli González, Claudia
dc.contributor.authorLeppänen, Marja H.
dc.contributor.authorVeijalainen, Aapo
dc.contributor.authorSallinen, Taisa
dc.contributor.authorEloranta, Aino-Maija
dc.contributor.authorEkelund, Ulf
dc.contributor.authorSchwab, Ursula
dc.contributor.authorBrage, Soren
dc.contributor.authorAtalay, Mustafa
dc.contributor.authorLakka, Timo A.
dc.date.accessioned2021-02-23T12:36:24Z
dc.date.available2021-02-23T12:36:24Z
dc.date.issued2022
dc.identifier.citationHaapala, E. A., Väistö, J., Ihalainen, J. K., Tomaselli González, C., Leppänen, M. H., Veijalainen, A., Sallinen, T., Eloranta, A.-M., Ekelund, U., Schwab, U., Brage, S., Atalay, M., & Lakka, T. A. (2022). Associations of physical activity, sedentary time, and diet quality with biomarkers of inflammation in children. <i>European Journal of Sport Science</i>, <i>22</i>(6), 906-915. <a href="https://doi.org/10.1080/17461391.2021.1892830" target="_blank">https://doi.org/10.1080/17461391.2021.1892830</a>
dc.identifier.otherCONVID_51603254
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/74362
dc.description.abstractWe investigated the associations of physical activity (PA), sedentary time (ST), and diet quality with biomarkers of inflammation in 390 children (192 girls, 198 boys) aged 6-8 years. PA energy expenditure (PAEE), light PA, moderate PA (MPA), vigorous PA (VPA), moderate-to-vigorous PA (MVPA), and ST were assessed by combined movement and heart rate sensor. Finnish Children Healthy Eating Index was calculated using data from 4 d food records. Body fat percentage (BF%) was measured by dual-energy X-ray absorptiometry. High-sensitivity C-reactive protein (Hs-CRP), leptin, interleukin-6 (IL-6), adiponectin, tumour necrosis factor-α, and glycoprotein acetyls were measured from fasting blood samples. PAEE, MPA, VPA, and MVPA were inversely associated with hs-CRP (β=-191 to -139, 95% CI=-0.294 to -0.024), leptin (β=-0.409 to -0.301, 95% CI=-0.499 to -0.107), IL-6 (β=-0.136 to -0.104, 95% CI=-0.240 to -0.001) and PAEE, MPA, and MVPA were inversely associated with glycoprotein acetyls (β=-0.117 to -0.103, 95% CI=-0.213 to -0.001). ST was directly associated with hs-CRP (β=0.170, 95% CI=0.070 to 0.269), leptin (β=0.355, 95% CI=0.265 to 0.445), and IL-6 (β=0.105, 95% CI=0.005 to 0.205). VPA was inversely associated with hs-CRP, leptin, and IL-6 in children with higher BF% (β=-0.344 to -0.181, 95% CI=-0.477 to -0.033) but not among children with lower BF% (β=-0.007 to 0.033, 95% CI=-0.183 to 0.184). In conclusion, PA was inversely and ST directly associated with circulating levels of biomarkers of inflammation among children. Furthermore, we observed that PA was inversely associated with these biomarkers for inflammation in children with a higher BF%.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherTaylor & Francis
dc.relation.ispartofseriesEuropean Journal of Sport Science
dc.rightsCC BY-NC-ND 4.0
dc.subject.otherinflammation
dc.subject.otherbiomarkers
dc.subject.otheryouth
dc.subject.otherexercise
dc.subject.othernutrition
dc.subject.otherobesity
dc.titleAssociations of physical activity, sedentary time, and diet quality with biomarkers of inflammation in children
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202102231748
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineLiikuntalääketiedefi
dc.contributor.oppiaineLiikuntafysiologiafi
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineSports and Exercise Medicineen
dc.contributor.oppiaineExercise Physiologyen
dc.contributor.oppiaineBiomechanicsen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange906-915
dc.relation.issn1746-1391
dc.relation.numberinseries6
dc.relation.volume22
dc.type.versionacceptedVersion
dc.rights.copyright© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group
dc.rights.accesslevelopenAccessfi
dc.subject.ysofyysinen aktiivisuus
dc.subject.ysokuntoliikunta
dc.subject.ysolihavuus
dc.subject.ysokehonkoostumus
dc.subject.ysoruokavaliot
dc.subject.ysotulehdus
dc.subject.ysobiomarkkerit
dc.subject.ysolapset (ikäryhmät)
dc.subject.ysoravinto
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p23102
jyx.subject.urihttp://www.yso.fi/onto/yso/p3708
jyx.subject.urihttp://www.yso.fi/onto/yso/p823
jyx.subject.urihttp://www.yso.fi/onto/yso/p26989
jyx.subject.urihttp://www.yso.fi/onto/yso/p3790
jyx.subject.urihttp://www.yso.fi/onto/yso/p1049
jyx.subject.urihttp://www.yso.fi/onto/yso/p12288
jyx.subject.urihttp://www.yso.fi/onto/yso/p4354
jyx.subject.urihttp://www.yso.fi/onto/yso/p3671
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.relation.doi10.1080/17461391.2021.1892830
jyx.fundinginformationThe PANIC Study has financially been supported by Ministry of Education and Culture of Finland, Ministry of Social Affairs and Health of Finland, Research Committee of the Kuopio University Hospital Catchment Area (State Research Funding), Finnish Innovation Fund Sitra, Social Insurance Institution of Finland, Finnish Cultural Foundation, Foundation for Paediatric Research, Diabetes Research Foundation in Finland, Finnish Foundation for Cardiovascular Research, Juho Vainio Foundation, Paavo Nurmi Foundation, Yrjö Jahnsson Foundation, and the city of Kuopio. Moreover, the PhD students and postdoctoral researchers of The PANIC Study have been supported by Program for Clinical Research and Program for Health Sciences of Doctoral School of University of Eastern Finland, Finnish Doctoral Programs in Public Health, Päivikki and Sakari Sohlberg Foundation, Paulo Foundation, Jalmari and Rauha Ahokas Foundation, Aarne and Aili Turunen Foundation, Finnish Medical Foundation, Jenny and Antti Wihuri Foundation, Kuopio Naturalists' Society, Olvi Foundation, and the city of Kuopio. SB was supported by UK Medical Research Council (MC_UU_12015/3) and the NIHR Biomedical Research Centre Cambridge [IS-BRC-1215-20014]. The sponsors had no role in designing the study, the collection, analysis, or interpretation of the data, the writing of the report, or the decision to submit the manuscript for publication.
dc.type.okmA1


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