Recent Submissions

  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia 

    Verhoeven, Virginie; Hysi, Pirro; Wojciechowski, Robert; QiaoFan; Guggenheim, Jeremy; Höhn, Rene; Macgregor, Stuart; Hewitt, Alex; Nag, Abhishek; Cheng, Ching-Yu; Yonova-Doing, Ekaterina; Zhou, Xin; Ikram, Kamran; Buitendijk, Gabrielle; McMahon, George; Kemp, John; Pourcain, Beate; Simpson, Claire; Mäkelä, Kari-Matti; Pärssinen, Olavi (Nature Publishing Group, 2013)
    Refractive error is the most common eye disorder worldwide and is a prominent cause of blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The CREAM consortium conducted genome-wide meta-analyses, ...
  • Persistence or Change in Leisure-Time Physical Activity Habits and Waist Gain During Early Adulthood: A Twin-Study 

    Rottensteiner, Mirva; Pietiläinen, Kirsi H.; Kaprio, Jaakko; Kujala, Urho (Wiley-Blackwell; TheObesity Society, 2014)
    Objective To determine the relationship between persistence or change in leisure‐time physical activity habits and waist gain among young adults. Methods Population‐based cohort study among 3383 Finnish twin individuals ...
  • Genome-wide association analysis identifies six new loci associated with forced vital capacity 

    Loth, Daan W; Artigas, María Soler; Gharib, Sina A; Wain, Louise V; Franceschini, Nora; Koch, Beate; Pottinger, Tess D; Smith, Albert Vernon; Duan, Qing; Oldmeadow, Chris; Lee, Mi Kyeong; Strachan, David P; James, Alan L; Huffman, Jennifer E; Vitart, Veronique; Ramasamy, Adaikalavan; Wareham, Nicholas J; Kaprio, Jaakko; Wang, Xin-Qun; Trochet, Holly; Kähönen, Mika; Flexeder, Claudia; Albrecht, Eva; Lopez, Lorna M; Jong, Kim de; Rantanen, Taina (Nature Publishing Group, 2014)
    Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 ...
  • G×E Interaction Influences Trajectories of Hand Grip Strength 

    Petersen, Inge; Pedersen, Nancy L.; Rantanen, Taina; Kremen, William S.; Johnson, Wendy; Panizzon, Matthew S.; Christiansen, Lene; Franz, Carol E.; McGue, Matt; Christensen, Kaare; Hamdi, Nayla R.; Krueger, Robert F.; Reynolds, Chandra (Springer US; Behavior Genetics Association, 2016)
    Age-related decline in grip strength predicts later life disability, frailty, lower well-being and cognitive change. While grip strength is heritable, genetic influence on change in grip strength has been relatively ignored, ...
  • A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol 

    Surakka, Ida; Whitfield, JB; Perola, M; Visscher, PM; Montgomery, GW; Falchi, M; Willemsen, G; Geus, EJC de; Magnusson, PKE; Christensen, K; Sorense, TIA; Pietiläinen, KH; Rantanen, Taina; Silander, K; Widén, E; Muilu, J; Rahman, I; Liljedahl, U; Syvänen, A-C; Palotie, A; Kaprio, J; Kyvik, KO; Pedersen, NL; Boomsma, DI; Spector, T; Martin, NG; Ripatti, S; Peltonen, L (Cambridge University Press, 2012)
    Genome-wide association analysis on monozygotic twin-pairs offers a route to discovery of gene–environment interactions through testing for variability loci associated with sensitivity to individual environment/lifestyle. ...

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