Show simple item record

dc.contributor.authorKesäniemi, Jenni
dc.contributor.authorLavrinienko, Anton
dc.contributor.authorTukalenko, Eugene
dc.contributor.authorMappes, Tapio
dc.contributor.authorWatts, Phillip C.
dc.contributor.authorJurvansuu, Jaana
dc.date.accessioned2020-01-15T08:19:34Z
dc.date.available2020-01-15T08:19:34Z
dc.date.issued2020
dc.identifier.citationKesäniemi, J., Lavrinienko, A., Tukalenko, E., Mappes, T., Watts, P. C., & Jurvansuu, J. (2020). Infection Load and Prevalence of Novel Viruses Identified from the Bank Vole Do Not Associate with Exposure to Environmental Radioactivity. <i>Viruses</i>, <i>12</i>(1), Article 44. <a href="https://doi.org/10.3390/v12010044" target="_blank">https://doi.org/10.3390/v12010044</a>
dc.identifier.otherCONVID_34063785
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/67315
dc.description.abstractBank voles (Myodes glareolus) are host to many zoonotic viruses. As bank voles inhabiting areas contaminated by radionuclides show signs of immunosuppression, resistance to apoptosis, and elevated DNA repair activity, we predicted an association between virome composition and exposure to radionuclides. To test this hypothesis, we studied the bank vole virome in samples of plasma derived from animals inhabiting areas of Ukraine (contaminated areas surrounding the former nuclear power plant at Chernobyl, and uncontaminated areas close to Kyiv) that differed in level of environmental radiation contamination. We discovered four strains of hepacivirus and four new virus sequences: two adeno-associated viruses, an arterivirus, and a mosavirus. However, viral prevalence and viral load, and the ability to cause a systemic infection, was not dependent on the level of environmental radiation.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherMDPI AG
dc.relation.ispartofseriesViruses
dc.rightsCC BY 4.0
dc.subject.otherplasma viromes
dc.subject.otherbank vole
dc.subject.otheradeno-associated virus
dc.subject.othermosavirus
dc.subject.otherarterivirus
dc.subject.otherenvironmental radiation
dc.subject.othernext-generation sequencing
dc.titleInfection Load and Prevalence of Novel Viruses Identified from the Bank Vole Do Not Associate with Exposure to Environmental Radioactivity
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202001151263
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineEkologia ja evoluutiobiologiafi
dc.contributor.oppiaineEcology and Evolutionary Biologyen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.relation.issn1999-4915
dc.relation.numberinseries1
dc.relation.volume12
dc.type.versionpublishedVersion
dc.rights.copyright© 2019 by the authors. Licensee MDPI, Basel, Switzerland
dc.rights.accesslevelopenAccessfi
dc.relation.grantnumber324605
dc.relation.grantnumber324602
dc.relation.grantnumber268670
dc.subject.ysosekvensointi
dc.subject.ysovirukset
dc.subject.ysometsämyyrä
dc.subject.ysosäteilybiologia
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p25917
jyx.subject.urihttp://www.yso.fi/onto/yso/p1123
jyx.subject.urihttp://www.yso.fi/onto/yso/p513
jyx.subject.urihttp://www.yso.fi/onto/yso/p1781
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.3390/v12010044
dc.relation.funderSuomen Akatemiafi
dc.relation.funderSuomen Akatemiafi
dc.relation.funderSuomen Akatemiafi
dc.relation.funderAcademy of Finlanden
dc.relation.funderAcademy of Finlanden
dc.relation.funderAcademy of Finlanden
jyx.fundingprogramAkatemiahanke, SAfi
jyx.fundingprogramAkatemiahanke, SAfi
jyx.fundingprogramAkatemiahanke, SAfi
jyx.fundingprogramAcademy Project, AoFen
jyx.fundingprogramAcademy Project, AoFen
jyx.fundingprogramAcademy Project, AoFen
jyx.fundinginformationThis research was funded by Kone foundation grant to J.J. and by the Finnish Academy to PCW (287153, 324602) and TM (268670, 324605).


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

CC BY 4.0
Except where otherwise noted, this item's license is described as CC BY 4.0