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dc.contributor.authorHaapanen, M. J.
dc.contributor.authorPerälä, M. M.
dc.contributor.authorOsmond, C.
dc.contributor.authorSalonen, M. K.
dc.contributor.authorKajantie, E.
dc.contributor.authorRantanen, Taina
dc.contributor.authorSimonen, M.
dc.contributor.authorPohjolainen, P.
dc.contributor.authorEriksson, J. G.
dc.contributor.authorvon Bonsdorff, Mikaela
dc.date.accessioned2019-10-02T10:16:48Z
dc.date.available2019-10-02T10:16:48Z
dc.date.issued2019
dc.identifier.citationHaapanen, M. J., Perälä, M.M., Osmond, C., Salonen, M. K., Kajantie, E., Rantanen, T., Simonen, M., Pohjolainen, P., Eriksson, J. G., & von Bonsdorff, M. (2019). Infant and childhood growth and frailty in old age : the Helsinki Birth Cohort Study. <i>Aging Clinical and Experimental Research</i>, <i>31</i>(5), 717-721. <a href="https://doi.org/10.1007/s40520-018-1011-0" target="_blank">https://doi.org/10.1007/s40520-018-1011-0</a>
dc.identifier.otherCONVID_28184936
dc.identifier.otherTUTKAID_78386
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/65726
dc.description.abstractBackground Evidence from life course studies highlights the importance of infant and childhood growth as risk factors for adulthood chronic diseases. Methods In this sub-study of the Helsinki Birth Cohort Study, we studied 1078 individuals who had both information on body size from birth to 12 years of age and who were assessed for frailty according to the Fried criteria at the mean age of 71 years. Results Greater BMI gain between 2 and 11 years in boys was associated with frailty in old age (age-adjusted RRR 2.36, 95% CI 1.21, 4.63). No similar associations were observed in girls. Conclusions Men who were frail in old age experienced accelerated BMI gain in childhood compared with those men who were not frail. This was not observed in women, which suggests that the patterns of early growth predisposing to frailty may vary by sex.fi
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofseriesAging Clinical and Experimental Research
dc.rightsIn Copyright
dc.subject.otherfrailty
dc.subject.otherlife course
dc.subject.otherrisk factor
dc.titleInfant and childhood growth and frailty in old age : the Helsinki Birth Cohort Study
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201909274276
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineGerontologia ja kansanterveysfi
dc.contributor.oppiaineGerontologian tutkimuskeskusfi
dc.contributor.oppiaineHyvinvoinnin tutkimuksen yhteisöfi
dc.contributor.oppiaineGerontology and Public Healthen
dc.contributor.oppiaineGerontology Research Centeren
dc.contributor.oppiaineSchool of Wellbeingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2019-09-27T09:15:10Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange717-721
dc.relation.issn1594-0667
dc.relation.numberinseries5
dc.relation.volume31
dc.type.versionacceptedVersion
dc.rights.copyright© Springer Nature Switzerland AG 2018
dc.rights.accesslevelopenAccessfi
dc.subject.ysovarhaislapsuus
dc.subject.ysolapsuus
dc.subject.ysopituuskasvu
dc.subject.ysopainonnousu
dc.subject.ysovanhuus
dc.subject.ysoelämänkaari
dc.subject.ysogerastenia
dc.subject.ysoriskitekijät
dc.subject.ysokasvu
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p18627
jyx.subject.urihttp://www.yso.fi/onto/yso/p13735
jyx.subject.urihttp://www.yso.fi/onto/yso/p21998
jyx.subject.urihttp://www.yso.fi/onto/yso/p21484
jyx.subject.urihttp://www.yso.fi/onto/yso/p6490
jyx.subject.urihttp://www.yso.fi/onto/yso/p3313
jyx.subject.urihttp://www.yso.fi/onto/yso/p28376
jyx.subject.urihttp://www.yso.fi/onto/yso/p13277
jyx.subject.urihttp://www.yso.fi/onto/yso/p5789
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.1007/s40520-018-1011-0
dc.type.okmA1


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