Show simple item record

dc.contributor.authorRohde, Christine
dc.contributor.authorResch, Grégory
dc.contributor.authorPirnay, Jean-Paul
dc.contributor.authorBlasdel, Bob G.
dc.contributor.authorDebarbieux, Laurent
dc.contributor.authorGelman, Daniel
dc.contributor.authorGórski, Andrzej
dc.contributor.authorHazan, Ronen
dc.contributor.authorHuys, Isabelle
dc.contributor.authorKakabadze, Elene
dc.contributor.authorŁobocka, Małgorzata
dc.contributor.authorMaestri, Alice
dc.contributor.authorDe Freitas Almeida, Gabriel
dc.contributor.authorMakalatia, Khatuna
dc.contributor.authorMalik, Danish J.
dc.contributor.authorMašlaňová, Ivana
dc.contributor.authorMerabishvili, Maia
dc.contributor.authorPantucek, Roman
dc.contributor.authorRose, Thomas
dc.contributor.authorŠtveráková, Dana
dc.contributor.authorRaemdonck, Hilde Van
dc.contributor.authorVerbeken, Gilbert
dc.contributor.authorChanishvili, Nina
dc.date.accessioned2018-04-17T11:32:34Z
dc.date.available2018-04-17T11:32:34Z
dc.date.issued2018
dc.identifier.citationRohde, C., Resch, G., Pirnay, J.-P., Blasdel, B. G., Debarbieux, L., Gelman, D., Górski, A., Hazan, R., Huys, I., Kakabadze, E., Łobocka, M., Maestri, A., De Freitas Almeida, G., Makalatia, K., Malik, D. J., Mašlaňová, I., Merabishvili, M., Pantucek, R., Rose, T., . . . Chanishvili, N. (2018). Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strain. <i>Viruses</i>, <i>10</i>(4), Article 178. <a href="https://doi.org/10.3390/v10040178" target="_blank">https://doi.org/10.3390/v10040178</a>
dc.identifier.otherCONVID_27997599
dc.identifier.otherTUTKAID_77340
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/57655
dc.description.abstractPhage therapy is increasingly put forward as a “new” potential tool in the fight against antibiotic resistant infections. During the “Centennial Celebration of Bacteriophage Research” conference in Tbilisi, Georgia on 26–29 June 2017, an international group of phage researchers committed to elaborate an expert opinion on three contentious phage therapy related issues that are hampering clinical progress in the field of phage therapy. This paper explores and discusses bacterial phage resistance, phage training and the presence of prophages in bacterial production strains while reviewing relevant research findings and experiences. Our purpose is to inform phage therapy stakeholders such as policy makers, officials of the competent authorities for medicines, phage researchers and phage producers, and members of the pharmaceutical industry. This brief also points out potential avenues for future phage therapy research and development as it specifically addresses those overarching questions that currently call for attention whenever phages go into purification processes for application.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofseriesViruses
dc.subject.otherresistance
dc.subject.otheradaptation
dc.subject.otherprophage
dc.subject.otherregulation
dc.titleExpert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strain
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201804122053
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineSolu- ja molekyylibiologiafi
dc.contributor.oppiaineBiologisten vuorovaikutusten huippututkimusyksikköfi
dc.contributor.oppiaineNanoscience Centerfi
dc.contributor.oppiaineCell and Molecular Biologyen
dc.contributor.oppiaineCentre of Excellence in Biological Interactions Researchen
dc.contributor.oppiaineNanoscience Centeren
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2018-04-12T12:15:06Z
dc.type.coarhttp://purl.org/coar/resource_type/c_dcae04bc
dc.description.reviewstatuspeerReviewed
dc.relation.issn1999-4915
dc.relation.numberinseries4
dc.relation.volume10
dc.type.versionpublishedVersion
dc.rights.copyright© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the terms of the Creative Commons License.
dc.rights.accesslevelopenAccessfi
dc.subject.ysolääkeresistenssi
dc.subject.ysolääkesuunnittelu
dc.subject.ysotuotanto
dc.subject.ysobakteriofagit
dc.subject.ysofagiterapia
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p25181
jyx.subject.urihttp://www.yso.fi/onto/yso/p25180
jyx.subject.urihttp://www.yso.fi/onto/yso/p944
jyx.subject.urihttp://www.yso.fi/onto/yso/p25303
jyx.subject.urihttp://www.yso.fi/onto/yso/p29496
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.3390/v10040178
dc.type.okmA2


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the terms of the Creative Commons License.
Except where otherwise noted, this item's license is described as © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the terms of the Creative Commons License.