Näytä suppeat kuvailutiedot

dc.contributor.authorLinko, Veikko
dc.contributor.authorShen, Boxuan
dc.contributor.authorTapio, Kosti
dc.contributor.authorToppari, Jussi
dc.contributor.authorKostiainen, Mauri A.
dc.contributor.authorTuukkanen, Sampo
dc.date.accessioned2015-11-09T10:07:04Z
dc.date.available2015-11-09T10:07:04Z
dc.date.issued2015
dc.identifier.citationLinko, V., Shen, B., Tapio, K., Toppari, J., Kostiainen, M., & Tuukkanen, S. (2015). One-step large-scale deposition of salt-free DNA origami nanostructures. <em>Scientific Reports</em>, 5, 15634. <a href="http://dx.doi.org/10.1038/srep15634">doi:10.1038/srep15634</a>
dc.identifier.otherTUTKAID_67658
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/47605
dc.description.abstractDNA origami nanostructures have tremendous potential to serve as versatile platforms in selfassembly -based nanofabrication and in highly parallel nanoscale patterning. However, uniform deposition and reliable anchoring of DNA nanostructures often requires specific conditions, such as pre-treatment of the chosen substrate or a fine-tuned salt concentration for the deposition buffer. In addition, currently available deposition techniques are suitable merely for small scales. In this article, we exploit a spray-coating technique in order to resolve the aforementioned issues in the deposition of different 2D and 3D DNA origami nanostructures. We show that purified DNA origamis can be controllably deposited on silicon and glass substrates by the proposed method. The results are verified using either atomic force microscopy or fluorescence microscopy depending on the shape of the DNA origami. DNA origamis are successfully deposited onto untreated substrates with surface coverage of about 4 objects/mm2 . Further, the DNA nanostructures maintain their shape even if the salt residues are removed from the DNA origami fabrication buffer after the folding procedure. We believe that the presented one-step spray-coating method will find use in various fields of material sciences, especially in the development of DNA biochips and in the fabrication of metamaterials and plasmonic devices through DNA metallisation.
dc.language.isoeng
dc.publisherNature Publishing Group
dc.relation.ispartofseriesScientific Reports
dc.subject.otherDNA nanostructures
dc.subject.otherDNA origamis
dc.subject.otherspray-coating
dc.titleOne-step large-scale deposition of salt-free DNA origami nanostructures
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201511063609
dc.contributor.laitosFysiikan laitosfi
dc.contributor.laitosDepartment of Physicsen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.identifier.doi10.1038/srep15634
dc.date.updated2015-11-06T13:15:18Z
dc.type.coarjournal article
dc.description.reviewstatuspeerReviewed
dc.relation.issn2045-2322
dc.relation.volume5
dc.type.versionpublishedVersion
dc.rights.copyright© 2015 the Authors. Published by Nature Publishing Group. This is an open access article licensed under a Creative Commons Attribution 4.0 International License.
dc.rights.accesslevelopenAccessfi
dc.rights.urlhttp://creativecommons.org/licenses/by/4.0/


Aineistoon kuuluvat tiedostot

Thumbnail

Aineisto kuuluu seuraaviin kokoelmiin

Näytä suppeat kuvailutiedot

© 2015 the Authors. Published by Nature Publishing Group. This is an open access article licensed under a Creative Commons Attribution 4.0 International License.
Ellei muuten mainita, aineiston lisenssi on © 2015 the Authors. Published by Nature Publishing Group. This is an open access article licensed under a Creative Commons Attribution 4.0 International License.