Applications of DNA self-assembled structures in nanoelectronics and plasmonics
In this thesis, the potential applications of DNA self-assembled structures were
explored in both nanoelectronics and plasmonics. The works can be divided into
two parts: electrical characterization of unmodified multilayered DNA origami and
DNA-gold-nanoparticle conjugates after they were trapped between gold nanoelectrodes by dielectrophoresis, and the development of a novel fabrication method using DNA origami as a template for smooth, high resolution metallic nanostructures
as well as optical characterization of them.
One of the biggest challenges in self-assembled nanoelectronic devices is to
connect them to macroscopic circuits. Dielectrophoretic (DEP) trapping has been
used extensively in manipulation of micro- and nanoscale objects in solution. We
have demonstrated this technique by trapping four structurally distinct multilayered DNA origami between gold nanoelectrodes by DEP and electrically characterized some of the trapped structures at high relative humidity. Most of the samples
showed insulating behavior in both DC I-V measurement and AC impedance spectroscopy. In the other experiment, an assembly of three gold nanoparticles (AuNPs)
conjugated with a triple-cross-over-tile (TX-tile) structure were designed, synthesized, and trapped by DEP. At the beginning no current was observed, but after
a few chemical gold growth steps, Coulomb blockade behavior was observed from
the liquid helium temperature up to the room temperature. Although no gated measurement was carried out, the random switching at low temperature measurements
highly resembled a similar behavior of single electron transistor (SET).
The second half of this thesis is focused on the development of a DNA-assisted
lithography (DALI) method, in which DNA origami was used to mask the growth
of SiO2 on Si chips in order to generate a stencil mask with openings of the DNA
origami shape. Then the stencil was used in conventional microfabrication processes
to deposit metallic nanostructures with almost the same shape as DNA origami
on different substrates. Three different DNA origami were used to fabricate metallic structures with various optical properties on sapphire substrates. The localized
surface plasmon resonance (LSPR) of Seeman tile and a bowtie antenna was characterized by a dark-field microscope. The surface enhanced Raman spectroscopy
(SERS) of two different marker molecules on gold bowtie antennas was characterized too. Finally, the chiral double-L samples landed on a surface with different orientation combinations showed distinct circular dichroism (CD) spectra. In addition,
a method to deposit DNA origami on unmodified surface with large area by spray
coating technique was reported.
...


Publisher
University of JyväskyläISBN
978-951-39-7380-3ISSN Search the Publication Forum
0075-465XKeywords
Metadata
Show full item recordCollections
- Väitöskirjat [3295]
Related items
Showing items with similar title or keywords.
-
Studies of two-dimensional and three-dimensional phononic crystal structures
Tian, Yolan (University of Jyväskylä, 2016)This thesis focuses on studying phononic crystal structures. More specifically, it is aimed at fabrication and measurement of thermal properties of two-dimensional (2D) periodic microstructures and three-dimensional (3D) ... -
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
Piskunen, Petteri; Shen, Boxuan; Julin, Sofia; Ijäs, Heini; Toppari, Jussi J.; Kostiainen, Mauri A.; Linko, Veikko (MyJove Corp., 2019)Structural DNA nanotechnology provides a viable route for building from the bottom-up using DNA as construction material. The most common DNA nanofabrication technique is called DNA origami, and it allows high-throughput ... -
Structural stability of DNA origami nanostructures under application-specific conditions
Ramakrishnan, Saminathan; Ijäs, Heini; Linko, Veikko; Keller, Adrian (Research Network of Computational and Structural Biotechnology, 2018)With the introduction of the DNA origami technique, it became possible to rapidly synthesize almost arbitrarily shaped molecular nanostructures at nearly stoichiometric yields. The technique furthermore provides ... -
Molecular devices for nanoelectronics and plasmonics
Kuzyk, Anton (University of Jyväskylä, 2009)This thesis is focused on fabrication and characterization of molecular devices. In connection with molecular electronics the dielectrophoresis based method for trapping and attaching nanoscale double-stranded DNA between ... -
Dielectrophoresis as an assembly method for carbon nanotube memory elements
Isoniemi, Tommi (2010)The experiments described in this Master's thesis aim to assess the practicality of using dielectrophoresis (DEP) for assembling memory elements from carbon nanotubes (CNTs). These elements were field-effect transistors ...