Näytä suppeat kuvailutiedot

dc.contributor.authorHuelsmann, Sven
dc.contributor.authorYlänne, Jari
dc.contributor.authorBrown, Nicholas H.
dc.date.accessioned2013-11-26T08:09:30Z
dc.date.available2013-11-26T08:09:30Z
dc.date.issued2013
dc.identifier.citationHuelsmann, S., Ylänne, J., & Brown, N. H. (2013). Filopodia-like actin cables position nuclei in association with perinuclear actin in Drosophila nurse cells. <i>Developmental Cell</i>, <i>26</i>(6), 604-615. <a href="https://doi.org/10.1016/j.devcel.2013.08.014" target="_blank">https://doi.org/10.1016/j.devcel.2013.08.014</a>
dc.identifier.otherCONVID_22877979
dc.identifier.otherTUTKAID_58221
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/42510
dc.description.abstractControlling the position of the nucleus is vital for a number of cellular processes from yeast to humans. In Drosophila nurse cells, nuclear positioning is crucial during dumping, when nurse cells contract and expel their contents into the oocyte. We provide evidence that in nurse cells, continuous filopodia-like actin cables, growing from the plasma membrane and extending to the nucleus, achieve nuclear positioning. These actin cables move nuclei away from ring canals. When nurse cells contract, actin cables associate laterally with the nuclei, in some cases inducing nuclear turning so that actin cables become partially wound around the nuclei. Our data suggest that a perinuclear actin meshwork connects actin cables to nuclei via actin-crosslinking proteins such as the filamin Cheerio. We provide a revised model for how actin structures position nuclei in nurse cells, employing evolutionary conserved machinery.fi
dc.language.isoeng
dc.publisherCell Press
dc.relation.ispartofseriesDevelopmental Cell
dc.relation.urihttp://linkinghub.elsevier.com/retrieve/pii/S1534-5807(13)00483-8
dc.subject.otherDrosophila
dc.subject.otheraktiini
dc.subject.otherDrospphila
dc.subject.otheractin
dc.titleFilopodia-like actin cables position nuclei in association with perinuclear actin in Drosophila nurse cells
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201311262642
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineSolu- ja molekyylibiologiafi
dc.contributor.oppiaineCell and Molecular Biologyen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2013-11-26T04:30:05Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange604-615
dc.relation.issn1534-5807
dc.relation.numberinseries6
dc.relation.volume26
dc.type.versionpublishedVersion
dc.rights.copyright© 2013 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.accesslevelopenAccessfi
dc.subject.ysokehitysbiologia
jyx.subject.urihttp://www.yso.fi/onto/yso/p18588
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/3.0/
dc.relation.doi10.1016/j.devcel.2013.08.014
dc.type.okmA1


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Näytä suppeat kuvailutiedot

© 2013 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ellei muuten mainita, aineiston lisenssi on © 2013 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.