Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator
| dc.contributor.author | Sitsanidis, E. D. | |
| dc.contributor.author | Kasapidou, P. M. | |
| dc.contributor.author | Hiscock, J. R. | |
| dc.contributor.author | Gubala, V. | |
| dc.contributor.author | Castel, H. | |
| dc.contributor.author | Popoola, P. I. A. | |
| dc.contributor.author | Hall, A. J. | |
| dc.contributor.author | Edwards, A. A. | |
| dc.date.accessioned | 2022-09-14T05:27:25Z | |
| dc.date.available | 2022-09-14T05:27:25Z | |
| dc.date.issued | 2022 | |
| dc.identifier.citation | Sitsanidis, E. D., Kasapidou, P. M., Hiscock, J. R., Gubala, V., Castel, H., Popoola, P. I. A., Hall, A. J., & Edwards, A.A. (2022). Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator. <i>Organic and Biomolecular Chemistry</i>, <i>20</i>(37), 7458-7466. <a href="https://doi.org/10.1039/d2ob01339h" target="_blank">https://doi.org/10.1039/d2ob01339h</a> | |
| dc.identifier.other | CONVID_156477791 | |
| dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/83234 | |
| dc.description.abstract | Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells. | en |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | eng | |
| dc.publisher | Royal Society of Chemistry (RSC) | |
| dc.relation.ispartofseries | Organic and Biomolecular Chemistry | |
| dc.rights | CC BY 4.0 | |
| dc.title | Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator | |
| dc.type | article | |
| dc.identifier.urn | URN:NBN:fi:jyu-202209144580 | |
| dc.contributor.laitos | Kemian laitos | fi |
| dc.contributor.laitos | Department of Chemistry | en |
| dc.contributor.oppiaine | Fysikaalinen kemia | fi |
| dc.contributor.oppiaine | Nanoscience Center | fi |
| dc.contributor.oppiaine | Physical Chemistry | en |
| dc.contributor.oppiaine | Nanoscience Center | en |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
| dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
| dc.description.reviewstatus | peerReviewed | |
| dc.format.pagerange | 7458-7466 | |
| dc.relation.issn | 1477-0520 | |
| dc.relation.numberinseries | 37 | |
| dc.relation.volume | 20 | |
| dc.type.version | publishedVersion | |
| dc.rights.copyright | © The Royal Society of Chemistry 2022 | |
| dc.rights.accesslevel | openAccess | fi |
| dc.subject.yso | biologinen aktiivisuus | |
| dc.subject.yso | syöpäsolut | |
| dc.subject.yso | orgaaniset yhdisteet | |
| dc.subject.yso | geelit | |
| dc.subject.yso | glioblastooma | |
| dc.format.content | fulltext | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p24582 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p23898 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p3841 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p12973 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p26613 | |
| dc.rights.url | https://creativecommons.org/licenses/by/4.0/ | |
| dc.relation.doi | 10.1039/d2ob01339h | |
| jyx.fundinginformation | E. D. S. would like to thank the University of Kent for his PhD scholarship and the Jane and Aatos Erkko Foundation for financial support during the writing of the current manuscript. J. R. H. would like to thank the UKRI for funding (MR/T020415/1). | |
| dc.type.okm | A1 |
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