Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator
Sitsanidis, E. D., Kasapidou, P. M., Hiscock, J. R., Gubala, V., Castel, H., Popoola, P. I. A., Hall, A. J., & Edwards, A.A. (2022). Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator. Organic and Biomolecular Chemistry, 20(37), 7458-7466. https://doi.org/10.1039/d2ob01339h
Julkaistu sarjassa
Organic and Biomolecular ChemistryPäivämäärä
2022Tekijänoikeudet
© The Royal Society of Chemistry 2022
Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells.
Julkaisija
Royal Society of Chemistry (RSC)ISSN Hae Julkaisufoorumista
1477-0520Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/156477791
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E. D. S. would like to thank the University of Kent for his PhD scholarship and the Jane and Aatos Erkko Foundation for financial support during the writing of the current manuscript. J. R. H. would like to thank the UKRI for funding (MR/T020415/1).Lisenssi
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