Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator
Sitsanidis, E. D., Kasapidou, P. M., Hiscock, J. R., Gubala, V., Castel, H., Popoola, P. I. A., Hall, A. J., & Edwards, A.A. (2022). Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator. Organic and Biomolecular Chemistry, 20(37), 7458-7466. https://doi.org/10.1039/d2ob01339h
Published in
Organic and Biomolecular ChemistryDate
2022Copyright
© The Royal Society of Chemistry 2022
Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells.
Publisher
Royal Society of Chemistry (RSC)ISSN Search the Publication Forum
1477-0520Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/156477791
Metadata
Show full item recordCollections
Additional information about funding
E. D. S. would like to thank the University of Kent for his PhD scholarship and the Jane and Aatos Erkko Foundation for financial support during the writing of the current manuscript. J. R. H. would like to thank the UKRI for funding (MR/T020415/1).License
Except where otherwise noted, this item's license is described as CC BY 4.0