Life-space mobility in Parkinson’s disease : associations with motor and non-motor symptoms
Rantakokko, M., Iwarsson, S., Slaug, B., & Nilsson, M. H. (2019). Life-space mobility in Parkinson’s disease : associations with motor and non-motor symptoms. Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, 74(4), 507-512. https://doi.org/10.1093/gerona/gly074
Date
2019Discipline
Gerontologia ja kansanterveysGerontologian tutkimuskeskusHyvinvoinnin tutkimuksen yhteisöGerontology and Public HealthGerontology Research CenterSchool of WellbeingCopyright
© 2018 Oxford University Press
Background
To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD).
Methods
About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III), and freezing of gait (item 3, FOG-Qsa). Non-motor symptoms included depressive symptoms (GDS-15), pain, fatigue (NHP-EN), and global cognition (MoCA). Life-space mobility was assessed with the life-space assessment (LSA). Calculations included composite score (range 0–120; higher indicating better life-space mobility), independent life-space (range 0–5), assisted life-space (range 0–5), and maximal life-space (range 0–5). Associations were analyzed with linear regression models, adjusted for age, sex, and PD severity (Hoehn and Yahr).
Results
Mean life-space mobility score was 72.3 (SD = 28.8). Almost all participants (90%) reached the highest life-space level (beyond town). Half of these reached this level independently, while one-third were unable to move outside their bedroom without assistive devices or personal help. When adjusted for confounders, depressive symptoms, pain, and perceived walking difficulties was negatively associated with life-space mobility. In the multivariable model, only perceived walking difficulties were associated with life-space mobility.
Conclusions
Our findings indicate that perceived walking difficulties should be targeted to maintain or improve life-space mobility in people with PD. Depressive symptoms and pain may also merit consideration. More research is needed to elucidate the role of environmental and personal factors for life-space mobility in PD.
...
![showless](/themes/JYX2//images/showless.png)
![showmore](/themes/JYX2//images/showmore.png)
Publisher
Oxford University PressISSN Search the Publication Forum
1079-5006Keywords
Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/27993165
Metadata
Show full item recordCollections
- Liikuntatieteiden tiedekunta [3048]
Additional information about funding
This work was supported by a personal grants to (M.R.) from the Academy of Finland (grant number 285747); and Ministry of Education and Culture. The Home and Health in Parkinson’s Disease Project was funded to (M.H.N. and S.I.) from the Strategic Research Area in neuroscience at Lund University (MultiPark); the Swedish Research Council; the Ribbingska Foundation in Lund; the Greta and Johan Kock Foundation; the Swedish Association of Persons with Neurological Disabilities (N.H.R.); Norrbacka-Eugenia Foundation; NEURO Sweden; and the Swedish Parkinson Foundation. This work was conducted in the context of the Centre for Ageing and Supportive Environments (CASE), financed by the Swedish Research Council for Health Care, Working Life, and Welfare (Forte). The financial sponsors played no role in the design, execution, analysis or interpretation of data, or writing of the study.![showless](/themes/JYX2//images/showless.png)
![showmore](/themes/JYX2//images/showmore.png)
License
Related items
Showing items with similar title or keywords.
-
Associations of hearing difficulties, life-space mobility, quality of life and depressive symptoms among older adults
Polku, Hannele (Jyväskylän yliopisto, 2020)Difficulty in hearing is common among older adults and may complicate engagement in everyday life situations, thereby reducing quality of life. In this study, I examined cross-sectional and longitudinal associations between ... -
Timed up-and-go performance is associated with objectively measured life space in patients 3 months after ischemic stroke : a cross-sectional observational study
Rössler, Roland; Rommers, Nikki; Kim, Eun-Kyeong; Iendra, Laura; Sofios, Alexander; Giannouli, Eleftheria; Portegijs, Erja; Rantanen, Taina; Infanger, Denis; Bridenbaugh, Stephanie; Engelter, Stefan T.; Schmidt-Trucksäss, Arno; Weibel, Robert; Peters, Nils; Hinrichs, Timo (Springer Science and Business Media LLC, 2023)Background Stroke is a common cause of mobility limitation, including a reduction in life space. Life space is defined as the spatial extent in which a person moves within a specified period of time. We aimed to analyze ... -
The Association Between Transportation and Life-Space Mobility in Community-Dwelling Older People With or Without Walking Difficulties
Viljanen, Anne; Mikkola, Tuija; Rantakokko, Merja; Portegijs, Erja; Rantanen, Taina (Sage Publications, Inc., 2016)Objective: The aim of this study is to examine whether a persons’ most frequently used mode of transportation is associated with life-space mobility and whether the association differs between persons with or without walking ... -
Task Modifications in Walking Postpone Decline in Life-Space Mobility Among Community-Dwelling Older People: A 2-year Follow-up Study
Rantakokko, Merja; Portegijs, Erja; Viljanen, Anne; Iwarsson, Susanne; Rantanen, Taina (Gerontological Society of America; Oxford University Press, 2017)Background Task modification refers to performing a task differently than before. While task modification in walking may be a sign of looming walking difficulty, it may also be adaptive in and postpone the decline in ... -
Association of tenacious goal pursuit and flexible goal adjustment with out-of-home mobility among community-dwelling older people
Siltanen, Sini; Rantanen, Taina; Portegijs, Erja; Tourunen, Anu; Poranen-Clark, Taina; Eronen, Johanna; Saajanaho, Milla (Editrice Kurtis, 2019)Background: As people age, functional losses may limit the potential to get outside the home and participate in desired activities and community life. Coping with age-related losses has been reported to be important for ...