Näytä suppeat kuvailutiedot

dc.contributor.authorLavrinienko, Anton
dc.contributor.authorMappes, Tapio
dc.contributor.authorTukalenko, Eugene
dc.contributor.authorMousseau, Timothy A.
dc.contributor.authorMøller, Anders P.
dc.contributor.authorKnight, Rob
dc.contributor.authorMorton, James T.
dc.contributor.authorThompson, Luke R.
dc.contributor.authorWatts, Phillip C.
dc.date.accessioned2018-10-30T08:47:13Z
dc.date.available2018-10-30T08:47:13Z
dc.date.issued2018
dc.identifier.citationLavrinienko, A., Mappes, T., Tukalenko, E., Mousseau, T. A., Møller, A. P., Knight, R., Morton, J. T., Thompson, L. R., & Watts, P. C. (2018). Environmental radiation alters the gut microbiome of the bank vole Myodes glareolus. <i>ISME Journal</i>, <i>12</i>(11), 2801-2806. <a href="https://doi.org/10.1038/s41396-018-0214-x" target="_blank">https://doi.org/10.1038/s41396-018-0214-x</a>
dc.identifier.otherCONVID_28161530
dc.identifier.otherTUTKAID_78255
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/60010
dc.description.abstractGut microbiota composition depends on many factors, although the impact of environmental pollution is largely unknown. We used amplicon sequencing of bacterial 16S rRNA genes to quantify whether anthropogenic radionuclides at Chernobyl (Ukraine) impact the gut microbiome of the bank vole Myodes glareolus. Exposure to elevated levels of environmental radionuclides had no detectable effect on the gut community richness but was associated with an almost two-fold increase in the Firmicutes:Bacteroidetes ratio. Animals inhabiting uncontaminated areas had remarkably similar gut communities irrespective of their proximity to the nuclear power plant. Hence, samples could be classified to high-radiation or low-radiation sites based solely on microbial community with >90% accuracy. Radiation-associated bacteria had distinct inferred functional profiles, including pathways involved in degradation, assimilation and transport of carbohydrates, xenobiotics biodegradation, and DNA repair. Our results suggest that exposure to environmental radionuclides significantly alters vertebrate gut microbiota.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherNature Publishing Group
dc.relation.ispartofseriesISME Journal
dc.rightsCC BY 4.0
dc.subject.othergut microbiome
dc.subject.otherbank vole
dc.subject.otherenvironmental radionuclides
dc.titleEnvironmental radiation alters the gut microbiome of the bank vole Myodes glareolus
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201810264536
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineEkologia ja evoluutiobiologiafi
dc.contributor.oppiaineEcology and Evolutionary Biologyen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2018-10-26T09:15:13Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange2801-2806
dc.relation.issn1751-7362
dc.relation.numberinseries11
dc.relation.volume12
dc.type.versionpublishedVersion
dc.rights.copyright© 2018 the Authors
dc.rights.accesslevelopenAccessfi
dc.relation.grantnumber268670
dc.subject.ysosäteily
dc.subject.ysosuolistomikrobisto
dc.subject.ysometsämyyrä
dc.subject.ysosäteilybiologia
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p4150
jyx.subject.urihttp://www.yso.fi/onto/yso/p37925
jyx.subject.urihttp://www.yso.fi/onto/yso/p513
jyx.subject.urihttp://www.yso.fi/onto/yso/p1781
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1038/s41396-018-0214-x
dc.relation.funderSuomen Akatemiafi
dc.relation.funderResearch Council of Finlanden
jyx.fundingprogramAkatemiahanke, SAfi
jyx.fundingprogramAcademy Project, AoFen
jyx.fundinginformationThe project was funded by the Academy of Finland (project numbers 287153 and 268670, to PCW and TM) and by an open-research doctoral program award (to AL) from the University of Oulu Graduate School. Additional support to TAM was provided by the Samuel Freeman Charitable Trust and by the Samuel Lawrence Foundation to LRT. JTM was supported under NSF-GRFP DGE-1144086.
dc.type.okmA1


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