Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence

Siitonen, Juha; Yu, Lu; Danielsson, Jakob; Gregorio, Giovanni Di; Somfai, Peter

doi:10.1021/acs.joc.8b01540

dc.contributor.author	Siitonen, Juha
dc.contributor.author	Yu, Lu
dc.contributor.author	Danielsson, Jakob
dc.contributor.author	Gregorio, Giovanni Di
dc.contributor.author	Somfai, Peter
dc.date.accessioned	2018-09-26T09:40:07Z
dc.date.available	2019-07-18T21:35:22Z
dc.date.issued	2018
dc.identifier.citation	Siitonen, J., Yu, L., Danielsson, J., Gregorio, G. D., & Somfai, P. (2018). Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence. <i>Journal of Organic Chemistry</i>, <i>83</i>(18), 11318-11322. <a href="https://doi.org/10.1021/acs.joc.8b01540" target="_blank">https://doi.org/10.1021/acs.joc.8b01540</a>
dc.identifier.other	CONVID_28184757
dc.identifier.other	TUTKAID_78385
dc.identifier.uri	https://jyx.jyu.fi/handle/123456789/59681
dc.description.abstract	A short formal synthesis of ent-Cephalotaxine is achieved. The approach features a new Lewis acid mediated [2,3]-Stevens rearrangement of N-allylated prolineamide to generate a key quaternary stereogenic center. Additionally, a one-pot Parham–aldol sequence was developed to rapidly assembly two of the four rings in the cephalotaxine core.	fi
dc.format.mimetype	application/pdf
dc.language.iso	eng
dc.publisher	American Chemical Society
dc.relation.ispartofseries	Journal of Organic Chemistry
dc.rights	In Copyright
dc.subject.other	formal synthesis
dc.title	Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence
dc.type	article
dc.identifier.urn	URN:NBN:fi:jyu-201809214206
dc.contributor.laitos	Kemian laitos	fi
dc.contributor.laitos	Department of Chemistry	en
dc.contributor.oppiaine	Orgaaninen kemia	fi
dc.contributor.oppiaine	Organic Chemistry	en
dc.type.uri	http://purl.org/eprint/type/JournalArticle
dc.date.updated	2018-09-21T09:15:11Z
dc.type.coar	http://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatus	peerReviewed
dc.format.pagerange	11318-11322
dc.relation.issn	0022-3263
dc.relation.numberinseries	18
dc.relation.volume	83
dc.type.version	acceptedVersion
dc.rights.copyright	© American Chemical Society, 2018
dc.rights.accesslevel	openAccess	fi
dc.subject.yso	luonnonaineet
dc.subject.yso	alkaloidit
dc.subject.yso	kemiallinen synteesi
dc.format.content	fulltext
jyx.subject.uri	http://www.yso.fi/onto/yso/p6956
jyx.subject.uri	http://www.yso.fi/onto/yso/p11306
jyx.subject.uri	http://www.yso.fi/onto/yso/p8468
dc.rights.url	http://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi	10.1021/acs.joc.8b01540
dc.type.okm	A1

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Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence

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Samankaltainen aineisto

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