Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence
| dc.contributor.author | Siitonen, Juha | |
| dc.contributor.author | Yu, Lu | |
| dc.contributor.author | Danielsson, Jakob | |
| dc.contributor.author | Gregorio, Giovanni Di | |
| dc.contributor.author | Somfai, Peter | |
| dc.date.accessioned | 2018-09-26T09:40:07Z | |
| dc.date.available | 2019-07-18T21:35:22Z | |
| dc.date.issued | 2018 | |
| dc.identifier.citation | Siitonen, J., Yu, L., Danielsson, J., Gregorio, G. D., & Somfai, P. (2018). Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence. <i>Journal of Organic Chemistry</i>, <i>83</i>(18), 11318-11322. <a href="https://doi.org/10.1021/acs.joc.8b01540" target="_blank">https://doi.org/10.1021/acs.joc.8b01540</a> | |
| dc.identifier.other | CONVID_28184757 | |
| dc.identifier.other | TUTKAID_78385 | |
| dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/59681 | |
| dc.description.abstract | A short formal synthesis of ent-Cephalotaxine is achieved. The approach features a new Lewis acid mediated [2,3]-Stevens rearrangement of N-allylated prolineamide to generate a key quaternary stereogenic center. Additionally, a one-pot Parham–aldol sequence was developed to rapidly assembly two of the four rings in the cephalotaxine core. | fi |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | eng | |
| dc.publisher | American Chemical Society | |
| dc.relation.ispartofseries | Journal of Organic Chemistry | |
| dc.rights | In Copyright | |
| dc.subject.other | formal synthesis | |
| dc.title | Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence | |
| dc.type | article | |
| dc.identifier.urn | URN:NBN:fi:jyu-201809214206 | |
| dc.contributor.laitos | Kemian laitos | fi |
| dc.contributor.laitos | Department of Chemistry | en |
| dc.contributor.oppiaine | Orgaaninen kemia | fi |
| dc.contributor.oppiaine | Organic Chemistry | en |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
| dc.date.updated | 2018-09-21T09:15:11Z | |
| dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
| dc.description.reviewstatus | peerReviewed | |
| dc.format.pagerange | 11318-11322 | |
| dc.relation.issn | 0022-3263 | |
| dc.relation.numberinseries | 18 | |
| dc.relation.volume | 83 | |
| dc.type.version | acceptedVersion | |
| dc.rights.copyright | © American Chemical Society, 2018 | |
| dc.rights.accesslevel | openAccess | fi |
| dc.subject.yso | luonnonaineet | |
| dc.subject.yso | alkaloidit | |
| dc.subject.yso | kemiallinen synteesi | |
| dc.format.content | fulltext | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p6956 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p11306 | |
| jyx.subject.uri | http://www.yso.fi/onto/yso/p8468 | |
| dc.rights.url | http://rightsstatements.org/page/InC/1.0/?language=en | |
| dc.relation.doi | 10.1021/acs.joc.8b01540 | |
| dc.type.okm | A1 |
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