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dc.contributor.authorHietavala, Enni-Maria
dc.contributor.authorStout, Jeffrey R.
dc.contributor.authorFrassetto, Lynda A.
dc.contributor.authorPuurtinen, Risto
dc.contributor.authorPitkänen, Hannu
dc.contributor.authorSelänne, Harri
dc.contributor.authorSuominen, Harri
dc.contributor.authorMero, Antti
dc.date.accessioned2017-12-04T07:01:19Z
dc.date.available2017-12-04T07:01:19Z
dc.date.issued2017
dc.identifier.citationHietavala, E.-M., Stout, J. R., Frassetto, L. A., Puurtinen, R., Pitkänen, H., Selänne, H., Suominen, H., & Mero, A. (2017). Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and gender. <i>Applied Physiology, Nutrition and Metabolism</i>, <i>42</i>(12), 1330-1340. <a href="https://doi.org/10.1139/apnm-2017-0279" target="_blank">https://doi.org/10.1139/apnm-2017-0279</a>
dc.identifier.otherCONVID_27175331
dc.identifier.otherTUTKAID_74746
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/56100
dc.description.abstractDiet composition influences acid-base status of the body. This may become more relevant as renal functional capacity declines with aging. We examined the effects of low (LD) versus high dietary acid load (HD) on blood acid-base status and exercise performance. Participants included 22 adolescents, 33 young adults (YA), and 33 elderly (EL), who followed a 7-day LD and HD in a randomized order. At the end of both diet periods the subjects performed a cycle ergometer test (3 × 10 min at 35%, 55%, 75%, and (except EL) until exhaustion at 100% of maximal oxygen uptake). At the beginning of and after the diet periods, blood samples were collected at rest and after all workloads. Oxygen uptake, respiratory exchange ratio (RER), and heart rate (HR) were monitored during cycling. In YA and EL, bicarbonate (HCO3−) and base excess (BE) decreased over the HD period, and HCO3−, BE, and pH were lower at rest after HD compared with LD. In YA and EL women, HCO3− and BE were lower at submaximal workloads after HD compared with LD. In YA women, the maximal workload was 19% shorter and maximal oxygen uptake, RER, and HR were lower after HD compared with LD. Our data uniquely suggests that better renal function is associated with higher availability of bases, which may diminish exercise-induced acidosis and improve maximal aerobic performance. Differences in glomerular filtration rate between the subject groups likely explains the larger effects of dietary acid load in the elderly compared with younger subjects and in women compared with men.
dc.language.isoeng
dc.publisherNational Research Council Canada
dc.relation.ispartofseriesApplied Physiology, Nutrition and Metabolism
dc.subject.otherpotential renal acid load
dc.subject.otherdietary acid load
dc.subject.otheracid-base status
dc.subject.otherglomerular filtration rate
dc.subject.otheraging
dc.subject.otheraerobic exercise
dc.titleDietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and gender
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201711274380
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosPsykologian laitosfi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.laitosDepartment of Psychologyen
dc.contributor.oppiainePsykologiafi
dc.contributor.oppiaineLiikuntafysiologiafi
dc.contributor.oppiaineGerontologia ja kansanterveysfi
dc.contributor.oppiainePsychologyen
dc.contributor.oppiaineExercise Physiologyen
dc.contributor.oppiaineGerontology and Public Healthen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2017-11-27T07:15:13Z
dc.type.coarjournal article
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1330-1340
dc.relation.issn1715-5312
dc.relation.numberinseries12
dc.relation.volume42
dc.type.versionacceptedVersion
dc.rights.copyright© the Authors, 2017. This is a final draft version of an article whose final and definitive form has been published by National Research Council Canada. Published in this repository with the kind permission of the publisher.
dc.rights.accesslevelopenAccessfi
dc.subject.ysoalkaliniteetti
jyx.subject.urihttp://www.yso.fi/onto/yso/p28291
dc.relation.doi10.1139/apnm-2017-0279


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