Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and gender
Hietavala, E.-M., Stout, J. R., Frassetto, L. A., Puurtinen, R., Pitkänen, H., Selänne, H., Suominen, H., & Mero, A. (2017). Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and gender. Applied Physiology, Nutrition and Metabolism, 42(12), 1330-1340. https://doi.org/10.1139/apnm-2017-0279
Published in
Applied Physiology, Nutrition and MetabolismAuthors
Date
2017Discipline
PsykologiaLiikuntafysiologiaGerontologia ja kansanterveysPsychologyExercise PhysiologyGerontology and Public HealthCopyright
© the Authors, 2017. This is a final draft version of an article whose final and definitive form has been published by National Research Council Canada. Published in this repository with the kind permission of the publisher.
Diet composition influences acid-base status of the body. This may become more relevant as renal functional capacity declines with aging. We examined the effects of low (LD) versus high dietary acid load (HD) on blood acid-base status and exercise performance. Participants included 22 adolescents, 33 young adults (YA), and 33 elderly (EL), who followed a 7-day LD and HD in a randomized order. At the end of both diet periods the subjects performed a cycle ergometer test (3 × 10 min at 35%, 55%, 75%, and (except EL) until exhaustion at 100% of maximal oxygen uptake). At the beginning of and after the diet periods, blood samples were collected at rest and after all workloads. Oxygen uptake, respiratory exchange ratio (RER), and heart rate (HR) were monitored during cycling. In YA and EL, bicarbonate (HCO3−) and base excess (BE) decreased over the HD period, and HCO3−, BE, and pH were lower at rest after HD compared with LD. In YA and EL women, HCO3− and BE were lower at submaximal workloads after HD compared with LD. In YA women, the maximal workload was 19% shorter and maximal oxygen uptake, RER, and HR were lower after HD compared with LD. Our data uniquely suggests that better renal function is associated with higher availability of bases, which may diminish exercise-induced acidosis and improve maximal aerobic performance. Differences in glomerular filtration rate between the subject groups likely explains the larger effects of dietary acid load in the elderly compared with younger subjects and in women compared with men.
...


Publisher
National Research Council CanadaISSN Search the Publication Forum
1715-5312Keywords
Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/27175331
Metadata
Show full item recordCollections
Related items
Showing items with similar title or keywords.
-
Effects of 12-Week Low or Moderate Dietary Acid Intake on Acid–Base Status and Kidney Function at Rest and during Submaximal Cycling
Hietavala, Enni-Maria; Ihalainen, Johanna; Frassetto, Lynda A.; Schumann, Moritz; Eklund, Daniela; Pitkänen, Hannu; Häkkinen, Keijo; Mero, Antti (MDPI AG, 2018)Prolonged effects of dietary acid intake on acid–base status and kidney function have not yet been studied in an intervention study in healthy subjects. Dietary acid load can be estimated by calculating the potential renal ... -
Dietary acid load and acid-base balance in exercise and health from adolescence to late adulthood
Hietavala, Enni-Maria (University of Jyväskylä, 2018)This thesis investigated whether dietary acid load has either short-term (4 to 7 days) or prolonged (12 weeks) effects on acid-base status at rest and during submaximal and maximal aerobic exercise; whether the effects ... -
Low-protein vegetarian diet does not have a short-term effect on blood acid¿base status but raises oxygen consumption during submaximal cycling
Hietavala, Enni-Maria; Puurtinen, Risto; Kainulainen, Heikki; Mero, Antti A. (BioMed Central (BMC), 2012)Background. Acid–base balance refers to the equilibrium between acids and bases in the human body. Nutrition may affect acid–base balance and further physical performance. With the help of PRAL (potential renal acid ... -
Effects of exercise and dietary intervention on serum metabolites in men with insomnia symptoms : a 6-month randomized-controlled trial
Zhang, Xiaobo; Wang, Xiuqiang; Le, Shenglong; Ojanen, Xiaowei; Tan, Xiao; Wiklund, Petri; Cheng, Sulin (Ke Ai Publishing Communications Ltd., 2020)Accumulating evidence show that exercise and diet interventions are associated with improved sleep quality. Studies investigating the effects of exercise and dieting on circulating metabolomics in people with sleep disorders, ... -
Precision exercise medicine : predicting unfavourable status and development in the 20-m shuttle run test performance in adolescence with machine learning
Joensuu, Laura; Rautiainen, Ilkka; Äyrämö, Sami; Syväoja, Heidi J; Kauppi, Jukka-Pekka; Kujala, Urho M; Tammelin, Tuija H (BMJ Publishing Group, 2021)Objectives: To assess the ability to predict individual unfavourable future status and development in the 20m shuttle run test (20MSRT) during adolescence with machine learning (random forest (RF) classifier). Methods: ...