Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates
Kiss, L., Nonn, M., Sillanpää, R., Fustero, S., & Fülöp, F. (2013). Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates. Beilstein Journal of Organic Chemistry, 9, 1164-1169. https://doi.org/10.3762/bjoc.9.130
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Beilstein Journal of Organic ChemistryDate
2013A regio- and stereoselective method has been developed for the synthesis of novel fluorinated 2-aminocyclohexanecarboxylic acid derivatives with the fluorine attached to position 4 of the ring. The synthesis starts from either cis- or trans-β-aminocyclohex-4-enecarboxylic acids and involves regio- and stereoselective transformation of the ring C–C double bond through iodooxazine formation and hydroxylation, followed by hydroxy–fluorine or oxo–fluorine exchange.
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Beilstein - Institut zur Foerderung der Chemischen WissenschaftenISSN Search the Publication Forum
1860-5397
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http://www.beilstein-journals.org/bjoc/home/home.htmPublication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/23006295
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