Morphological characterization of neuronal and non-neuronal phenotypes of the human neuroblastoma SH-SY5Y cell line
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The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
Eesmaa, Ave; Yu, Li-Ying; Göös, Helka; Nõges, Kristofer; Kovaleva, Vera; Hellman, Maarit; Zimmermann, Richard; Jung, Martin; Permi, Perttu; Varjosalo, Markku; Lindholm, Päivi; Saarma, Mart (Elsevier, 2021)Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an ER-stress regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and ... -
Consistency of Targeted Metatranscriptomics and Morphological Characterization of Phytoplankton Communities
Vuorio, Kristiina; Mäki, Anita; Salmi, Pauliina; Aalto, Sanni L.; Tiirola, Marja (Frontiers Media, 2020)The composition of phytoplankton community is the basis for environmental monitoring and assessment of the ecological status of aquatic ecosystems. Community composition studies of phytoplankton have been based on ... -
Pathogenic mechanisms of how human parvovirus breaks self-tolerance
Puttaraksa, Kanoktip (University of Jyväskylä, 2017)It is known that viral infections can cause acute, chronic, and autoimmune diseases (ADs). However, the mechanism of how a persistent viral infection contributes to ADs remains still unclear. In this thesis, pathological ...