Showing items with similar title or keywords.

• The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor 

  Eesmaa, Ave; Yu, Li-Ying; Göös, Helka; Nõges, Kristofer; Kovaleva, Vera; Hellman, Maarit; Zimmermann, Richard; Jung, Martin; Permi, Perttu; Varjosalo, Markku; Lindholm, Päivi; Saarma, Mart (Elsevier, 2021)

  Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an ER-stress regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and ...

• Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins 

  Bulanova, Daria; Ianevski, Aleksandr; Bugai, Andrii; Akimov, Yevhen; Kuivanen, Suvi; Paavilainen, Henrik; Kakkola, Laura; Nandania, Jatin; Turunen, Laura; Ohman, Tiina; Ala-Hongisto, Hanna; Pesonen, Hanna M.; Kuisma, Marika S.; Honkimaa, Anni; Walton, Emma L.; Oksenych, Valentyn; Lorey, Martina B.; Guschin, Dmitry; Shim, Jungmin; Kim, Jinhee; Than, Thoa T.; Chang, So Young; Hukkanen, Veijo; Kulesskiy, Evgeny; Marjomäki, Varpu; Julkunen, Ilkka; Nyman, Tuula A.; Matikainen, Sampsa; Saarela, Jani S.; Sane, Famara; Hober, Didier; Gabriel, Gülsah; De Brabander, Jef K.; Martikainen, Miika; Windisch, Marc P.; Min, Ji-Young; Bruzzone, Roberto; Aittokallio, Tero; Vähä-Koskela, Markus; Vapalahti, Olli; Pulk, Arto; Velagapudi, Vidya; Kainov, Denis E. (MDPI, 2017)

  Viral diseases remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral diseases, new treatments are urgently needed. Here we show that small-molecules, ...

• Calreticulin 3 gene polymorphism in celiac disease and effects of gluten on calreticulin localization and expression in epithelial cells in vitro 

  Siltanen, Antti (2008)

• VEGF-B as a target for cancer therapy : characterization of monoclonal antibodies towards VEGF-B and generation of VEGF-B expressing tumour cell lines 

  Ollila, Hanna (2007)

• Pathogenic mechanisms of how human parvovirus breaks self-tolerance 

  Puttaraksa, Kanoktip (University of Jyväskylä, 2017)

  It is known that viral infections can cause acute, chronic, and autoimmune diseases (ADs). However, the mechanism of how a persistent viral infection contributes to ADs remains still unclear. In this thesis, pathological ...