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dc.contributor.authorLaamanen, Suvi E.
dc.contributor.authorEloranta, Aino-Maija
dc.contributor.authorHaapala, Eero A.
dc.contributor.authorSallinen, Taisa
dc.contributor.authorSchwab, Ursula
dc.contributor.authorLakka, Timo A.
dc.date.accessioned2024-01-11T10:02:28Z
dc.date.available2024-01-11T10:02:28Z
dc.date.issued2024
dc.identifier.citationLaamanen, S. E., Eloranta, A.-M., Haapala, E. A., Sallinen, T., Schwab, U., & Lakka, T. A. (2024). Associations of diet quality and food consumption with serum biomarkers for lipid and amino acid metabolism in Finnish children : the PANIC study. <i>European Journal of Nutrition</i>, <i>63</i>(2), 623-637. <a href="https://doi.org/10.1007/s00394-023-03293-8" target="_blank">https://doi.org/10.1007/s00394-023-03293-8</a>
dc.identifier.otherCONVID_197505840
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/92676
dc.description.abstractPurpose To investigate the associations of overall diet quality and dietary factors with serum biomarkers for lipid and amino acid metabolism in a general population of children. Methods We studied 194 girls and 209 boys aged 6–8 years participating in the Physical Activity and Nutrition in Children study. Food consumption was assessed by 4-day food records and diet quality was quantified by the Finnish Children Healthy Eating Index (FCHEI). Fasting serum fatty acids, amino acids, apolipoproteins, as well as lipoprotein particle sizes were analyzed with high-throughput nuclear magnetic resonance spectroscopy. Data were analyzed using linear regression adjusted for age, sex, and body fat percentage. Results FCHEI was directly associated with the ratio of polyunsaturated (PUFA) to saturated fatty acids (SFA) (PUFA/SFA), the ratio of PUFA to monounsaturated fatty acids (MUFA) (PUFA/MUFA), the ratio of PUFA to total fatty acids (FA) (PUFA%), the ratio of omega-3-fatty acids to total FA (omega-3 FA%), and inversely associated with the ratio of MUFA to total FA (MUFA%), alanine, glycine, histidine and very-low density lipoprotein (VLDL) particle size. Consumption of vegetable oils and vegetable-oil-based margarine (≥ 60% fat) was directly associated with PUFA/SFA, PUFA/MUFA, PUFA%, the ratio of omega-6 FA to total FA (omega-6 FA%), and inversely associated with SFA, MUFA, SFA to total FA (SFA%), MUFA%, alanine and VLDL particle size. Consumption of high-fiber grain products directly associated with PUFA/SFA, PUFA/MUFA, omega-3 FA%, omega-6 FA%, PUFA% and inversely associated with SFA and SFA%. Fish consumption directly related to omega-3 FA and omega-3 FA%. Consumption of sugary products was directly associated with histidine and VLDL particle size. Vegetable, fruit, and berry consumption had direct associations with VLDL particle size and the ratio of apolipoprotein B to apolipoprotein A1. Consumption of low fat (< 1%) milk was directly associated with phenylalanine. A higher consumption of high-fat (≥ 1%) milk was associated with lower serum MUFA/SFA and higher SFA%. Sausage consumption was directly related to SFA% and histidine. Red meat consumption was inversely associated with glycine. Conclusions Better diet quality, higher in intake of dietary sources of unsaturated fat and fiber, and lower in sugary product intake were associated with more favorable levels of serum biomarkers for lipid and amino acid metabolism independent of adiposity.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofseriesEuropean Journal of Nutrition
dc.rightsCC BY 4.0
dc.subject.otherdiet
dc.subject.otherfatty acids
dc.subject.otheramino acids
dc.subject.otherapolipoproteins
dc.subject.otherlipoprotein particle size
dc.subject.otherchildren
dc.titleAssociations of diet quality and food consumption with serum biomarkers for lipid and amino acid metabolism in Finnish children : the PANIC study
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202401111177
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineLiikuntalääketiedefi
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineSports and Exercise Medicineen
dc.contributor.oppiaineBiomechanicsen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange623-637
dc.relation.issn1436-6207
dc.relation.numberinseries2
dc.relation.volume63
dc.type.versionpublishedVersion
dc.rights.copyright© The Author(s) 2023
dc.rights.accesslevelopenAccessfi
dc.subject.ysoruokavaliot
dc.subject.ysoaminohapot
dc.subject.ysoaineenvaihdunta
dc.subject.ysorasvahapot
dc.subject.ysoravitsemus
dc.subject.ysorasvat
dc.subject.ysolapset (ikäryhmät)
dc.subject.ysoterveysvaikutukset
dc.subject.ysoproteiinit
dc.subject.ysoapolipoproteiinit
dc.subject.ysolipoproteiinit
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p3790
jyx.subject.urihttp://www.yso.fi/onto/yso/p9530
jyx.subject.urihttp://www.yso.fi/onto/yso/p3066
jyx.subject.urihttp://www.yso.fi/onto/yso/p4800
jyx.subject.urihttp://www.yso.fi/onto/yso/p5748
jyx.subject.urihttp://www.yso.fi/onto/yso/p4153
jyx.subject.urihttp://www.yso.fi/onto/yso/p4354
jyx.subject.urihttp://www.yso.fi/onto/yso/p15449
jyx.subject.urihttp://www.yso.fi/onto/yso/p4332
jyx.subject.urihttp://www.yso.fi/onto/yso/p19808
jyx.subject.urihttp://www.yso.fi/onto/yso/p18874
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1007/s00394-023-03293-8
jyx.fundinginformationOpen access funding provided by University of Eastern Finland (including Kuopio University Hospital). The PANIC study has been supported financially by grants from Ministry of Education and Culture of Finland, Ministry of Social Affairs and Health of Finland, Academy of Finland, Research Committee of the Kuopio University Hospital Catchment Area (State Research Funding), Finnish Innovation Fund Sitra, Social Insurance Institution of Finland, Finnish Cultural Foundation, Foundation for Paediatric Research, Diabetes Research Foundation in Finland, Finnish Foundation for Cardiovascular Research, Juho Vainio Foundation, Paavo Nurmi Foundation, Yrjö Jahnsson Foundation, and the city of Kuopio. The funding sources have not been involved in designing the study, collecting the data, analyzing the data, interpreting the results, writing the manuscript, or deciding to submit the paper for publication.
dc.type.okmA1


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