Exercise as therapy for neurodevelopmental and cognitive dysfunction in people with a Fontan circulation : A narrative review
Verrall, C. E., Tran, D. L., Yang, J. Y.-M., Lubans, D. R., Winlaw, D. S., Ayer, J., Celermajer, D., & Cordina, R. (2023). Exercise as therapy for neurodevelopmental and cognitive dysfunction in people with a Fontan circulation : A narrative review. Frontiers in Pediatrics, 11, Article 1111785. https://doi.org/10.3389/fped.2023.1111785
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Frontiers in PediatricsDate
2023Copyright
© 2023 Verrall, Tran, Yang, Lubans, Winlaw,
Ayer, Celermajer and Cordina
People with a Fontan circulation are at risk of neurodevelopmental delay and disability, and cognitive dysfunction, that has significant implications for academic and occupational attainment, psychosocial functioning, and overall quality of life. Interventions for improving these outcomes are lacking. This review article discusses current intervention practices and explores the evidence supporting exercise as a potential intervention for improving cognitive functioning in people living with a Fontan circulation. Proposed pathophysiological mechanisms underpinning these associations are discussed in the context of Fontan physiology and avenues for future research are recommended.
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https://converis.jyu.fi/converis/portal/detail/Publication/177804008
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Additional information about funding
This study was supported by the NSW Health Cardiovascular Research Capacity Program—Early-Mid Career Researcher Grant (Ref: H21/174585). DT was supported by the Medical Research Future Fund—Cardiovascular Health Mission—Congenital Heart Disease Grant (ARGCHDG000016). JY receives positional funding from the Royal Children's Hospital Foundation (Grant number: RCHF 2022-1402).License
Except where otherwise noted, this item's license is described as CC BY 4.0