Näytä suppeat kuvailutiedot

dc.contributor.authorHaapala, Eero A.
dc.contributor.authorTompuri, Tuomo
dc.contributor.authorLintu, Niina
dc.contributor.authorViitasalo, Anna
dc.contributor.authorSavonen, Kai
dc.contributor.authorLakka, Timo A.
dc.contributor.authorLaukkanen, Jari A.
dc.date.accessioned2022-11-09T11:26:36Z
dc.date.available2022-11-09T11:26:36Z
dc.date.issued2022
dc.identifier.citationHaapala, E. A., Tompuri, T., Lintu, N., Viitasalo, A., Savonen, K., Lakka, T. A., & Laukkanen, J. A. (2022). Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?. <i>Journal of Science and Medicine in Sport</i>, <i>25</i>(11), 923-929. <a href="https://doi.org/10.1016/j.jsams.2022.08.002" target="_blank">https://doi.org/10.1016/j.jsams.2022.08.002</a>
dc.identifier.otherCONVID_151050203
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/83836
dc.description.abstractObjectives Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches with cardiometabolic risk factors between children and adults. We therefore investigated these associations in children and adults using same measures for CRF and cardiometabolic risk factors. Design Cross-sectional. Methods A total of 352 children (47.2 % girls) and 572 men were included in the study. Peak oxygen uptake (V̇O2peak) was measured during a maximal exercise test on a cycle ergometer and was scaled by total body mass (BM−1), total fat free mass (FFM−1), and allometrically modelled BM, FFM, and stature. Insulin, glucose, triglycerides, HDL cholesterol, and LDL cholesterol were assessed from fasting blood samples and systolic and diastolic blood pressure were measured. HOMA-IR and continuous metabolic risk score were computed. Results V̇O2peak scaled by BM−1 was inversely associated with insulin, HOMA-IR, triglycerides, diastolic blood pressure, the cardiometabolic risk score and the number of cardiometabolic risk factors in children and adults. However, these associations attenuated remarkably when V̇O2peak was scaled by total FFM or allometrically modelled BM, FFM, or stature. V̇O2peak was consistently and positively associated with HDL cholesterol in children and adults irrespective of the scaling approach. Conclusions The inverse associations of CRF with cardiometabolic risk factors among children and adults attenuated remarkably when body size and composition were appropriately controlled for. However, the positive association between CRF and HDL cholesterol was consistent irrespective of the scaling approach.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofseriesJournal of Science and Medicine in Sport
dc.rightsCC BY 4.0
dc.subject.otherfitness
dc.subject.othermetabolic syndrome
dc.subject.otherinsulin resistance
dc.subject.otherpaediatrics
dc.subject.otherobesity
dc.subject.otherbody composition
dc.titleIs low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202211095137
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineLiikuntalääketiedefi
dc.contributor.oppiaineBiomechanicsen
dc.contributor.oppiaineSports and Exercise Medicineen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange923-929
dc.relation.issn1440-2440
dc.relation.numberinseries11
dc.relation.volume25
dc.type.versionpublishedVersion
dc.rights.copyright© 2022 The Author(s). Published by Elsevier Ltd on behalf of Sports Medicine Australia
dc.rights.accesslevelopenAccessfi
dc.relation.grantnumber202200238
dc.subject.ysolihavuus
dc.subject.ysokolesteroli
dc.subject.ysoaikuiset
dc.subject.ysomittausmenetelmät
dc.subject.ysoennaltaehkäisy
dc.subject.ysoylipaino
dc.subject.ysolastentautioppi
dc.subject.ysoinsuliiniresistenssi
dc.subject.ysoHDL-kolesteroli
dc.subject.ysoaineenvaihduntahäiriöt
dc.subject.ysolapset (ikäryhmät)
dc.subject.ysoriskitekijät
dc.subject.ysoterveysvaikutukset
dc.subject.ysoLDL-kolesteroli
dc.subject.ysometabolinen oireyhtymä
dc.subject.ysokehonkoostumus
dc.subject.ysokunto
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p823
jyx.subject.urihttp://www.yso.fi/onto/yso/p10609
jyx.subject.urihttp://www.yso.fi/onto/yso/p5590
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jyx.subject.urihttp://www.yso.fi/onto/yso/p19552
jyx.subject.urihttp://www.yso.fi/onto/yso/p826
jyx.subject.urihttp://www.yso.fi/onto/yso/p3629
jyx.subject.urihttp://www.yso.fi/onto/yso/p22290
jyx.subject.urihttp://www.yso.fi/onto/yso/p16832
jyx.subject.urihttp://www.yso.fi/onto/yso/p6239
jyx.subject.urihttp://www.yso.fi/onto/yso/p4354
jyx.subject.urihttp://www.yso.fi/onto/yso/p13277
jyx.subject.urihttp://www.yso.fi/onto/yso/p15449
jyx.subject.urihttp://www.yso.fi/onto/yso/p14054
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jyx.subject.urihttp://www.yso.fi/onto/yso/p7383
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1016/j.jsams.2022.08.002
dc.relation.funderJuho Vainio Foundationen
dc.relation.funderJuho Vainion Säätiöfi
jyx.fundingprogramFoundationen
jyx.fundingprogramSäätiöfi
jyx.fundinginformationThe PANIC study has been supported financially by grants from Ministry of Education and Culture of Finland, Ministry of Social Affairs and Health of Finland, Research Committee of the Kuopio University Hospital Catchment Area (State Research Funding), Finnish Innovation Fund Sitra, Social Insurance Institution of Finland, Finnish Cultural Foundation, Foundation for Paediatric Research, Diabetes Research Foundation in Finland, Finnish Foundation for Cardiovascular Research, Juho Vainio Foundation, Paavo Nurmi Foundation, Yrjö Jahnsson Foundation, and the city of Kuopio. EAH and JAL have been supported by the Finnish Foundation for Cardiovascular Research.
dc.type.okmA1


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