Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?
Haapala, E. A., Tompuri, T., Lintu, N., Viitasalo, A., Savonen, K., Lakka, T. A., & Laukkanen, J. A. (2022). Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?. Journal of Science and Medicine in Sport, 25(11), 923-929. https://doi.org/10.1016/j.jsams.2022.08.002
Julkaistu sarjassa
Journal of Science and Medicine in SportTekijät
Päivämäärä
2022Tekijänoikeudet
© 2022 The Author(s). Published by Elsevier Ltd on behalf of Sports Medicine Australia
Objectives
Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches with cardiometabolic risk factors between children and adults. We therefore investigated these associations in children and adults using same measures for CRF and cardiometabolic risk factors.
Design
Cross-sectional.
Methods
A total of 352 children (47.2 % girls) and 572 men were included in the study. Peak oxygen uptake (V̇O2peak) was measured during a maximal exercise test on a cycle ergometer and was scaled by total body mass (BM−1), total fat free mass (FFM−1), and allometrically modelled BM, FFM, and stature. Insulin, glucose, triglycerides, HDL cholesterol, and LDL cholesterol were assessed from fasting blood samples and systolic and diastolic blood pressure were measured. HOMA-IR and continuous metabolic risk score were computed.
Results
V̇O2peak scaled by BM−1 was inversely associated with insulin, HOMA-IR, triglycerides, diastolic blood pressure, the cardiometabolic risk score and the number of cardiometabolic risk factors in children and adults. However, these associations attenuated remarkably when V̇O2peak was scaled by total FFM or allometrically modelled BM, FFM, or stature. V̇O2peak was consistently and positively associated with HDL cholesterol in children and adults irrespective of the scaling approach.
Conclusions
The inverse associations of CRF with cardiometabolic risk factors among children and adults attenuated remarkably when body size and composition were appropriately controlled for. However, the positive association between CRF and HDL cholesterol was consistent irrespective of the scaling approach.
...
Julkaisija
ElsevierISSN Hae Julkaisufoorumista
1440-2440Asiasanat
fitness metabolic syndrome insulin resistance paediatrics obesity body composition lihavuus kolesteroli aikuiset mittausmenetelmät ennaltaehkäisy ylipaino lastentautioppi insuliiniresistenssi HDL-kolesteroli aineenvaihduntahäiriöt lapset (ikäryhmät) riskitekijät terveysvaikutukset LDL-kolesteroli metabolinen oireyhtymä kehonkoostumus kunto
Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/151050203
Metadata
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Rahoittaja(t)
Juho Vainion SäätiöRahoitusohjelmat(t)
SäätiöLisätietoja rahoituksesta
The PANIC study has been supported financially by grants from Ministry of Education and Culture of Finland, Ministry of Social Affairs and Health of Finland, Research Committee of the Kuopio University Hospital Catchment Area (State Research Funding), Finnish Innovation Fund Sitra, Social Insurance Institution of Finland, Finnish Cultural Foundation, Foundation for Paediatric Research, Diabetes Research Foundation in Finland, Finnish Foundation for Cardiovascular Research, Juho Vainio Foundation, Paavo Nurmi Foundation, Yrjö Jahnsson Foundation, and the city of Kuopio. EAH and JAL have been supported by the Finnish Foundation for Cardiovascular Research. ...Lisenssi
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