Data from Estrogenic Regulation of Muscle Apoptosis (ERMA) study
Estrogeeni, vaihdevuodet ja toimintakyky (ERMA) -tutkimuksen aineisto
Laakkonen, Eija; Kovanen, Vuokko; Sipilä, Sarianna. Data from Estrogenic Regulation of Muscle Apoptosis (ERMA) study. 10.17011/jyx/dataset/83491
Contributors
Central Finland Health Care District; Kokko, Katja; Kujala, Urho; Tammelin, Tuija; Aukee, Pauliina; Jyväskylän ammattikorkeakoulu; Keski-Suomen sairaanhoitopiiri; Jyväskylä University of Applied SciencesDate
2022Access restrictions
Restricted use due to personal information protection. You can still contact author to ask for a copy of the material.
Copyright
Laakkonen, Eija and University of Jyväskylä
The multidisciplinary Estrogenic Regulation of Muscle Apoptosis (ERMA) study was designed to reveal how hormonal differences over the menopausal stages affect the physiological and psychological functioning of middle-aged women. In addition, health behaviour (e.g., physical activity and eating behaviour) and blood-based biomarkers are investigated. Biomarker data includes different omics datasets (e.g. metabolomics, genomics, transcriptomics). The complete data set includes baseline data collection and two different follow-ups. The baseline ERMA study (=parent data) is a population-based cohort study, which forms a parent data set for the follow-up studies (ERMA follow-up and EsmiRs). Data set includes 47 to 55 years old Caucasian women living in the city of Jyväskylä or neighboring municipalities in Finland. Population sample was drawn from The Finnish Population Information System (dvv.fi) and is described in Kovanen et al 2018 (doi: 10.1097/GME.0000000000001117). Data collection proceeded in different phases including several questionnaires, biological sampling (blood samples and muscle biopsies for a subset of participants) and laboratory measurements. Physical activity was assessed as self-reports via questionnaires and with accelerometer measurements (ActiGraph). Eating behaviour was assessed through structured questionnaires. Laboratory measurements included body composition measurements (DXA and Inbody), muscle strength (hand grip, knee extension), muscle power (vertical jump test) and paper-pen type of cognition measurements. The English translation of main questionnaire and the study flow indicating connections between baseline ERMA and its follow-ups (by 25.4.2022) are attached.
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Publication(s) related to the dataset
- Kovanen, V., Aukee, P., Kokko, K., Finni Juutinen, T., Tarkka, I., Tammelin, T., Kujala, U., Sipilä, S., & Laakkonen, E. (2018). Design and protocol of Estrogenic Regulation of Muscle Apoptosis (ERMA) study with 47 to 55-year-old women's cohort : novel results show menopause-related differences in blood count. Menopause: The Journal of The North American Menopause Society, 25(9), 1020-1032. https://doi.org/10.1097/GME.0000000000001117 https://jyx.jyu.fi/handle/123456789/59306
- Laakkonen, E., Kulmala, J., Aukee, P., Hakonen, H., Kujala, U., Lowe, D. A., Kovanen, V., Tammelin, T., & Sipilä, S. (2017). Female reproductive factors are associated with objectively measured physical activity in middle-aged women. PLoS ONE, 12(2), Article e0172054. https://doi.org/10.1371/journal.pone.0172054 https://jyx.jyu.fi/handle/123456789/53151
Dataset in research information system
https://converis.jyu.fi/converis/portal/detail/ResearchDataset/68768367
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Show full item recordCollections
- Tutkimusdata [284]
Related funder(s)
Academy of Finland; European Commission; Euroopan komissio; Suomen AkatemiaFunding program(s)
Academy Research Fellow, AoF; Akatemiahanke, SA; Akatemiatutkijan tutkimuskulut, SA; Research costs of Academy Research Fellow, AoF; Academy Project, AoF; Akatemiatutkija, SA; MSCA Marie Skłodowska-Curie Actions, H2020
The content of the publication reflects only the author’s view. The funder is not responsible for any use that may be made of the information it contains.
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