Interactive multiobjective optimization for finding the most preferred exercise therapy modality in knee osteoarthritis
Shavazipour, B., Afsar, B., Multanen, J., Miettinen, K., & Kujala, U. M. (2022). Interactive multiobjective optimization for finding the most preferred exercise therapy modality in knee osteoarthritis. Annals of Medicine, 54(1), 181-194. https://doi.org/10.1080/07853890.2021.2024876
Published inAnnals of Medicine
DisciplineFysioterapiaLaskennallinen tiedeLiikuntalääketiedeMultiobjective Optimization GroupPhysiotherapyComputational ScienceSports and Exercise MedicineMultiobjective Optimization Group
© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
Background: There are no explicit guidelines or tools available to support clinicians in selecting exercise therapy modalities according to the characteristics of individual patients despite the apparent need. Objective: This study develops a methodology based on a novel multiobjective optimization model and examines its feasibility as a decision support tool to support healthcare professionals in comparing different modalities and identifying the most preferred one based on a patient’s needs. Methods: Thirty-one exercise therapy modalities were considered from 21 randomized controlled trials. A novel interactive multiobjective optimization model was designed to characterize the efficacy of an exercise therapy modality based on five objectives: minimizing cost, maximizing pain reduction, maximizing disability improvement, minimizing the number of supervised sessions, and minimizing the length of the treatment period. An interactive model incorporates clinicians’ preferences in finding the most preferred exercise therapy modality for each need. Multiobjective optimization methods are mathematical algorithms designed to identify the optimal balance between multiple conflicting objectives among available solutions/alternatives. They explicitly evaluate the conflicting objectives and support decision-makers in identifying the best balance. An experienced research-oriented physiotherapist was involved as a decisionmaker in the interactive solution process testing the proposed decision support tool. Results: The proposed methodology design and interactive process of the tool, including preference information, graphs, and exercise suggestions following the preferences, can help clinicians to find the most preferred exercise therapy modality based on a patient’s needs and health status; paving the way to individualize recommendations. Conclusions: We examined the feasibility of our decision support tool using an interactive multiobjective optimization method designed to help clinicians balance between conflicting objectives to find the most preferred exercise therapy modality for patients with knee osteoarthritis. The proposed methodology is generic enough to be applied in any field of medical and healthcare settings, where several alternative treatment options exist. ...
PublisherTaylor & Francis
Publication in research information system
MetadataShow full item record
Related funder(s)Research Council of Finland
Funding program(s)Academy Project, AoF
Additional information about fundingThis research was partly funded by the Academy of Finland [grant no. 322221].
Showing items with similar title or keywords.
The effect of aquatic exercise on symptoms, function, body composition and cartilage in knee osteoarthritis Waller, Benjamin (University of Jyväskylä, 2016)Knee osteoarthritis (OA) is the most common joint disease associated with pain and loss of functional capacity. The management of knee OA is multifaceted and covers the whole OA continuum from injury prevention to the ...
Effect of Biomechanical Footwear on upper and lower leg muscle activity in comparison with knee brace and normal walking Ylinen, Jari; Pennanen, Antti; Weir, Adam; Häkkinen, Arja; Multanen, Juhani (Elsevier, 2021)Aim To evaluate the activity of knee stabilizing muscles while using custom-made biomechanical footwear (BF) and to compare it when walking barefoot and with a knee brace (Unloader®). Methods Seventeen healthy ...
Munukka, Matti (Jyväskylän yliopisto, 2018)
Effect of 12-month supervised, home-based physical exercise on functioning among persons with signs of frailty : Randomized Controlled Trial Suikkanen, Sara; Soukkio, Paula; Aartolahti, Eeva; Kääriä, Sanna; Kautiainen, Hannu; Hupli, Markku T.; Pitkälä, Kaisu; Sipilä, Sarianna; Kukkonen-Harjula, Katriina (Elsevier BV, 2021)Objectives To investigate the effects of a 12-month home-based exercise program on functioning and falls among persons with signs of frailty. Design A randomized controlled trial with a 1:1 allocation Setting Ho ...
Physical disability in community-dwelling older people after hip fracture : randomized controlled trials with physical rehabilitation Edgren, Johanna (University of Jyväskylä, 2013)