Longitudinal associations of physical activity, sedentary time, and cardiorespiratory fitness with arterial health in children : the PANIC study
Korhonen, M., Väistö, J., Veijalainen, A., Leppänen, M., Ekelund, U., Laukkanen, J. A., Brage, S., Lintu, N., Haapala, E. A., & Lakka, T. A. (2021). Longitudinal associations of physical activity, sedentary time, and cardiorespiratory fitness with arterial health in children : the PANIC study. Journal of Sports Sciences, 39(17), 1980-1987. https://doi.org/10.1080/02640414.2021.1912450
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We investigated the longitudinal associations of physical activity (PA), sedentary time (ST), and cardiorespiratory fitness (CRF) with arterial health among children. In our primary analyses, we investigated 245 children (girls 51.8%) aged 6-9 years participating in the baseline examinations who had data on arterial health at 2-year follow-up. We also utilized a subsample of 90 children who had a complete arterial health data at baseline and 2-year follow-up. ST (≤1.5 METs), light PA (>1.5-4 METs), moderate PA (>4-7 METs), vigorous PA (>7METs), and moderate-to-vigorous PA (MVPA, >4 METs) were assessed by combined movement and heart rate monitoring and CRF by maximal exercise testing on a cycle ergometer at baseline and 2-year follow-up. Stiffness index (SI) as a measure of arterial stiffness and change in reflection index during exercise test (DRI) as a measure of arterial dilation capacity were assessed by pulse contour analysis. Two-year change in vigorous PA was associated with DRI in boys but not in girls (p=0.021 for interaction). In a subsample analyses, 2-year changes in MPA, VPA, and MVPA were inversely associated with 2-year change in SI. In conclusion, promoting PA at higher intensities may confer larger benefits on arterial health than reducing ST and increasing LPA. ...
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Additional information about fundingThis work was supported by the Juho Vainion Säätiö [Na]; Kela [Na]; Lastentautien Tutkimussäätiö [Na]; Opetus- ja Kulttuuriministeriö [Na]; Diabetes Research Foundation in Finland [Na]; Finnish Innovation Fund Sitra [Na]; Research Committee of the Kuopio University Hospital Catchment Area [Na]; Paavo Nurmen Säätiö [Na]; Sosiaali- ja Terveysministeriö [Na]; Suomen Kulttuurirahasto [Na]; Sydäntutkimussäätiö [Na]; Yrjö Jahnssonin Säätiö [Na]. ...
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