Which indices of cardiorespiratory fitness are more strongly associated with brain health in children with overweight/obesity?
Haapala, E. A., Lubans, D. R., Jaakkola, T., Barker, A. R., Plaza‐Florido, A., Gracia‐Marco, L., Solis‐Urra, P., Cadenas‐Sanchez, C., Esteban‐Cornejo, I., & Ortega, F. B. (2024). Which indices of cardiorespiratory fitness are more strongly associated with brain health in children with overweight/obesity?. Scandinavian Journal of Medicine and Science in Sports, 34(1), Article e14549. https://doi.org/10.1111/sms.14549
Authors
Date
2024Discipline
LiikuntalääketiedeBiomekaniikkaLiikuntapedagogiikkaHyvinvoinnin tutkimuksen yhteisöSports and Exercise MedicineBiomechanicsSport PedagogySchool of WellbeingCopyright
© 2023 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd.
Purpose
To compare the strength of associations between different indices of cardiorespiratory fitness (CRF) and brain health outcomes in children with overweight/obesity.
Methods
Participants were 100 children aged 8–11 years. CRF was assessed using treadmill exercise test (peak oxygen uptake [V̇O2peak], treadmill time, and V̇O2 at ventilatory threshold) and 20-metre shuttle run test (20mSRT, laps, running speed, estimated V̇O2peak using the equations by Léger et al., Mahar et al., and Matsuzaka et al.). Intelligence, executive functions, and academic performance were assessed using validated methods. Total gray matter and hippocampal volumes were assessed using structural MRI.
Results
V̇O2peak/body mass (β = 0.18, 95% CI = 0.01–0.35) and treadmill time (β = 0.18–0.21, 95% CI = 0.01–0.39) were positively associated with gray matter volume. 20mSRT laps were positively associated with executive functions (β = 0.255, 95% CI = 0.089–0.421) and academic performance (β = 0.199–0.255, 95% CI = 0.006–0.421), and the running speed was positively associated with executive functions (β = 0.203, 95% CI = 0.039–0.367). Estimated V̇O2peak/Léger et al. was positively associated with intelligence, executive functions, academic performance, and gray matter volume (β = 0.205–0.282, 95% CI = 0.013–0.500). Estimated V̇O2peak/Mahar et al. and V̇O2peak/Matsuzaka et al. (speed) were positively associated with executive functions (β = 0.204–0.256, 95% CI = 0.031–0.436).
Conclusion
Although V̇O2peak is considered the gold standard indicator of CRF in children, peak performance (laps or running speed) and estimated V̇O2peak/Léger et al. derived from 20mSRT had stronger and more consistent associations with brain health outcomes than other indices of CRF in children with overweight/obesity.
...
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Wiley-BlackwellISSN Search the Publication Forum
0905-7188Keywords
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https://converis.jyu.fi/converis/portal/detail/Publication/197229308
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- Liikuntatieteiden tiedekunta [3151]
Additional information about funding
The present study was mainly supported by grants from the Spanish Ministry of Economy and Competitiveness (DEP2013- 47540, DEP2016- 79512- R, and DEP2017- 91544- EXP), European Regional Development Fund (ERDF), the European Commission (667302), and by the Alicia Koplowitz Foundation. Supplementary funding was obtained from the Andalusian Operational Programme supported with ERDF (FEDER in Spanish, B- CTS- 355- UGR18). This study was also supported by the University of Granada, Plan Propio de Investigación, Visiting Scholar grants and Excellence actions: Units of Excellence; Unit of Excellence on Exercise, Nutrition and Health (UCEENS) and by the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades and the ERDF (SOMM17/6107/UGR). IE- C is supported by the Spanish Ministry of Science and Innovation (RyC2019- 027287- 1). PS- U is supported by a grant from ANID/BECAS Chile/72180543 and through a Margarita Salas grant from the Spanish Ministry Universities. EAH was supported by the Juho Vainio Foundation. AP- F contribution was funded in part by NIH grant #: U01 TR002004 (REACH project). ...License
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