1,2‐Benzothiazine Derivatives from Sulfonimidamides by Metal‐Catalyzed Annulation Reactions in Solution and under Solvent‐Free Mechanochemical Conditions

Schöbel, Jan-Hendrik; Elbers, Philipp; Truong, Khai-Nghi; Rissanen, Kari; Bolm, Carsten

doi:10.1002/adsc.202001505

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Schöbel, J.-H., Elbers, P., Truong, K.-N., Rissanen, K., & Bolm, C. (2021). 1,2‐Benzothiazine Derivatives from Sulfonimidamides by Metal‐Catalyzed Annulation Reactions in Solution and under Solvent‐Free Mechanochemical Conditions. Advanced Synthesis and Catalysis, 363(5), 1322-1329. https://doi.org/10.1002/adsc.202001505

Julkaistu sarjassa

Advanced Synthesis and Catalysis

Tekijät

Schöbel, Jan-Hendrik |

Elbers, Philipp |

Truong, Khai-Nghi |

Rissanen, Kari |

Bolm, Carsten

Päivämäärä

2021

Oppiaine

Orgaaninen kemia Organic Chemistry

Tekijänoikeudet

Three‐dimensional aza‐analogues of 1,2‐benzothiazine 1,1‐dioxides have been prepared from sulfonimidamides. Two different protocols are presented. The first is a rhodium‐catalyzed annulation reaction with alpha‐sulfonyloxyketones leading to 4 unsubstituted benzothiazine derivatives. By selective bromination with NBS the heterocyclic ring can further be functionalized. In the second approach, an iridium catalyst is applied under solvent‐free mechanochemical conditions providing products with 3,4‐disubstituted thiazine rings from diazoketo esters and diazoketo sulfones.

Julkaisija

Wiley-VCH Verlag

ISSN Hae Julkaisufoorumista

1615-4150

Lisenssi

Ellei muuten mainita, aineiston lisenssi on CC BY 4.0

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