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dc.contributor.authorMessa, Guy A.M.
dc.contributor.authorPiasecki, Mathew
dc.contributor.authorRittweger, Jörn
dc.contributor.authorMcPhee, Jamie, S.
dc.contributor.authorKoltai, Erika
dc.contributor.authorRadak, Zsolt
dc.contributor.authorSimunic, Bostjan
dc.contributor.authorHeinonen, Ari
dc.contributor.authorSuominen, Harri
dc.contributor.authorKorhonen, Marko T.
dc.contributor.authorDegens, Hans
dc.date.accessioned2020-07-28T05:02:32Z
dc.date.available2020-07-28T05:02:32Z
dc.date.issued2020
dc.identifier.citationMessa, G. A., Piasecki, M., Rittweger, J., McPhee, J., Koltai, E., Radak, Z., Simunic, B., Heinonen, A., Suominen, H., Korhonen, M. T., & Degens, H. (2020). Absence of an aging‐related increase in fibre type grouping in athletes and non‐athletes. <i>Scandinavian Journal of Medicine and Science in Sports</i>, <i>30</i>(11), 2057-2069. <a href="https://doi.org/10.1111/sms.13778" target="_blank">https://doi.org/10.1111/sms.13778</a>
dc.identifier.otherCONVID_41642095
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/71250
dc.description.abstractThe ageing‐related loss of muscle mass is thought to be partly attributable to motor neuron loss and motor unit remodelling that result in fibre type grouping. We examined fibre type grouping in 19‐ to 85‐year‐old athletes and non‐athletes and evaluated to which extent any observed grouping is explained by the fibre type composition of the muscle. Since regular physical activity may stimulate reinnervation, we hypothesised that fibre groups are larger in master athletes than in age‐matched non‐athletes. Fibre type grouping was assessed in m. vastus lateralis biopsies from 22 young (19‐27 years) and 35 healthy older (66‐82 years) non‐athletes, and 14 young (20‐29 years), 51 middle‐aged (38‐65 years) and 31 older (66‐85 years) athletes. An ‘enclosed fibre’ was any muscle fibre of a particular type surrounded by fibres of the same type only. A fibre type group was defined as a group of fibres with at least one enclosed fibre. Only type II fibre cross‐sectional area (FCSA) showed an age‐related decline that was greater in athletes (p < 0.001) than in non‐athletes (p = 0.012). There was no significant age‐related effect on fibre group size or fibre group number in athletes or non‐athletes, and the observed grouping was similar to that expected from the fibre type composition. At face value these observations do 1) neither show evidence for an age‐related loss and remodelling of motor units nor 2) improved reinnervation with regular physical activity, but 3) histological examination may not reveal the full extent of ageing‐related motor unit remodelling.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofseriesScandinavian Journal of Medicine and Science in Sports
dc.rightsCC BY 4.0
dc.subject.otherageing
dc.subject.otherdenervation
dc.subject.otherfibre type
dc.subject.othergrouping
dc.subject.otherreinnervation
dc.subject.othervastus lateralis
dc.titleAbsence of an aging‐related increase in fibre type grouping in athletes and non‐athletes
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202007285399
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineGerontologia ja kansanterveysfi
dc.contributor.oppiaineFysioterapiafi
dc.contributor.oppiaineGerontology and Public Healthen
dc.contributor.oppiainePhysiotherapyen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange2057-2069
dc.relation.issn0905-7188
dc.relation.numberinseries11
dc.relation.volume30
dc.type.versionacceptedVersion
dc.rights.copyright© 2020 The Author(s)
dc.rights.accesslevelopenAccessfi
dc.subject.ysofyysinen aktiivisuus
dc.subject.ysolihassolut
dc.subject.ysolihasmassa
dc.subject.ysoikääntyminen
dc.subject.ysolihakset
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p23102
jyx.subject.urihttp://www.yso.fi/onto/yso/p25540
jyx.subject.urihttp://www.yso.fi/onto/yso/p29135
jyx.subject.urihttp://www.yso.fi/onto/yso/p5056
jyx.subject.urihttp://www.yso.fi/onto/yso/p2784
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1111/sms.13778
dc.type.okmA1


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