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• Estrogenic regulation of skeletal muscle proteome : a study of premenopausal women and postmenopausal MZ cotwins discordant for hormonal therapy 

  Laakkonen, Eija; Soliymani, Rabah; Karvinen, Sira; Kaprio, Jaakko; Kujala, Urho; Baumann, Marc; Sipilä, Sarianna; Kovanen, Vuokko; Lalowski, Maciej (Wiley-Blackwell Publishing Ltd, 2017)

  Female middle age is characterized by a decline in skeletal muscle mass and performance, predisposing women to sarcopenia, functional limitations, and metabolic dysfunction as they age. Menopausal loss of ovarian function ...

• Towards powerful old age : association between hormone replacement therapy and skeletal muscle 

  Ronkainen, Paula (University of Jyväskylä, 2010)

• Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement 

  Kangas, Reeta; Morsiani, Cristina; Pizza, Grazia; Lanzarini, Catia; Aukee, Pauliina; Kaprio, Jaakko; Sipilä, Sarianna; Franceschi, Claudio; Kovanen, Vuokko; Laakkonen, Eija; Capri, Miriam (Impact Journals, 2018)

  Tissue-specific effects of 17β-estradiol are delivered via both estrogen receptors and microRNAs (miRs). Menopause is known to affect the whole-body fat distribution in women. This investigation aimed at identifying ...

• Associations of Sex Hormones and Hormonal Status With Arterial Stiffness in a Female Sample From Reproductive Years to Menopause 

  Laakkonen, Eija K.; Karppinen, Jari E.; Lehti, Satu; Lee, Earric; Pesonen, Emilia; Juppi, Hanna-Kaarina; Kujala, Urho M.; Haapala, Eero A.; Aukee, Pauliina; Laukkanen, Jari A.; Ihalainen, Johanna K. (Frontiers Media SA, 2021)

  Objective: Loss of sex hormones has been suggested to underlie menopause-associated increment in cardiovascular risk. We investigated associations of sex hormones with arterial stiffness in 19–58-years-old women. We also ...

• DIFFERENTIAL INFLUENCE OF PERIPHERAL AND SYSTEMIC SEX STEROIDS ON SKELETAL MUSCLE QUALITY IN PRE- AND POSTMENOPAUSAL WOMEN. 

  Laakkonen, Eija; Sipilä, Sarianna; Alén, Markku; Ronkainen, Paula; Ankarberg-Lindgren, Carina; Puolakka, Jukka; Suominen, Harri; Hämäläinen, Esa; Turpeinen, Ursula; Konttinen, Yrjö; Kovanen, Vuokko (Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland, 2011)

  Aging is associated with gradual decline of skeletal muscle strength and mass often leading to diminished muscle quality. This phenomenon is known as sarcopenia and affects about 30% of the over 60-year-old population ...