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dc.contributor.authorOwen, Patrick J.
dc.contributor.authorMiller, Clint T.
dc.contributor.authorRantalainen, Timo
dc.contributor.authorSimson, Katherine J.
dc.contributor.authorConnell, David
dc.contributor.authorHahne, Andrew J.
dc.contributor.authorTrudel, Guy
dc.contributor.authorFord, Jon J.
dc.contributor.authorBelavy, Daniel L.
dc.date.accessioned2020-03-30T07:08:15Z
dc.date.available2020-03-30T07:08:15Z
dc.date.issued2020
dc.identifier.citationOwen, P. J., Miller, C. T., Rantalainen, T., Simson, K. J., Connell, D., Hahne, A. J., Trudel, G., Ford, J. J., & Belavy, D. L. (2020). Exercise for the intervertebral disc : a 6-month randomised controlled trial in chronic low back pain. <i>European Spine Journal</i>, <i>29</i>(8), 1887-1899. <a href="https://doi.org/10.1007/s00586-020-06379-7" target="_blank">https://doi.org/10.1007/s00586-020-06379-7</a>
dc.identifier.otherCONVID_35109411
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/68358
dc.description.abstractBackground context Muscle, bone and tendon respond anabolically to mechanical forces. Whether the intervertebral disc (IVD) can benefit from exercise is unclear. Purpose To examine whether exercise can beneficially affect IVD characteristics. Study design/setting This is a single-blinded 6-month randomised controlled trial (ACTRN12615001270505) in an exercise and physiotherapy clinic. Patient sample Forty patients with chronic non-specific low back pain (NSCLBP) are included in this study. Outcome measures The primary outcome was lumbar IVD T2 time (MRI). Secondary outcomes included IVD diffusion coefficient and IVD expansion with short-duration lying. Methods Twenty patients progressively loaded their lumbar IVDs (exercise) via an exercise programme involving progressive upright aerobic and resistance exercises targeting the trunk and major muscle groups and were compared to twenty patients who performed motor control training and manual therapy (control). Testing occurred at baseline, 3 months and 6 months. Results Seventeen exercise and fifteen control patients completed the interventions. There were no group-by-time differences in T2 time of the entire IVD (exercise 94.1 ± 10.0 ms vs. control 96.5 ± 9.3 ms, p = 0.549). Exercise patients had shorter T2 time in the posterior annulus at 6 months (82.7 ± 6.8 ms vs. 85.1 ± 8.0 ms, p = 0.028). Exercise patients showed higher L5/S1 apparent diffusion coefficients and decreased IVD height at 3 months (both p ≤ 0.050). After adjustments for multiple comparisons, differences lost statistical significance. Per-protocol and intent-to-treat analyses yielded similar findings. Conclusions This trial found that 6 months of exercise did not benefit the IVD of people with NSCLBP. Based on this index study, future studies could investigate the effect of exercise on IVD in different populations, with different types, durations and/or intensities of exercise, and using different IVD markers.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofseriesEuropean Spine Journal
dc.rightsIn Copyright
dc.subject.otherrehabilitation
dc.subject.otherphysical therapy
dc.subject.otherphysiotherapy
dc.subject.otherspine
dc.subject.othermagnetic resonance imaging
dc.subject.otherphysical activity
dc.subject.otherintervertebral disc
dc.titleExercise for the intervertebral disc : a 6-month randomised controlled trial in chronic low back pain
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202003302570
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineGerontologia ja kansanterveysfi
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineGerontologian tutkimuskeskusfi
dc.contributor.oppiaineHyvinvoinnin tutkimuksen yhteisöfi
dc.contributor.oppiaineGerontology and Public Healthen
dc.contributor.oppiaineBiomechanicsen
dc.contributor.oppiaineGerontology Research Centeren
dc.contributor.oppiaineSchool of Wellbeingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1887-1899
dc.relation.issn0940-6719
dc.relation.numberinseries8
dc.relation.volume29
dc.type.versionacceptedVersion
dc.rights.copyright© 2020 Springer Nature
dc.rights.accesslevelopenAccessfi
dc.subject.ysoselkäranka
dc.subject.ysofysioterapia
dc.subject.ysokuntoutus
dc.subject.ysonikamavälilevy
dc.subject.ysoliikunta
dc.subject.ysoliikuntahoito
dc.subject.ysomagneettikuvaus
dc.subject.ysofyysinen aktiivisuus
dc.subject.ysokrooninen kipu
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p110
jyx.subject.urihttp://www.yso.fi/onto/yso/p10515
jyx.subject.urihttp://www.yso.fi/onto/yso/p3320
jyx.subject.urihttp://www.yso.fi/onto/yso/p12862
jyx.subject.urihttp://www.yso.fi/onto/yso/p916
jyx.subject.urihttp://www.yso.fi/onto/yso/p7811
jyx.subject.urihttp://www.yso.fi/onto/yso/p12131
jyx.subject.urihttp://www.yso.fi/onto/yso/p23102
jyx.subject.urihttp://www.yso.fi/onto/yso/p16952
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.1007/s00586-020-06379-7
jyx.fundinginformationThis study was supported by internal institutional funding (Deakin University School of Exercise and Nutrition Sciences, reference number Belavy 2014–2017).
dc.type.okmA1


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