dc.contributor.author | Bell, Christina L. | |
dc.contributor.author | Rantanen, Taina | |
dc.contributor.author | Chen, Randi | |
dc.contributor.author | Davis, James | |
dc.contributor.author | Petrovitch, Helen | |
dc.contributor.author | Ross, G. Webster | |
dc.contributor.author | Masaki, Kamal | |
dc.date.accessioned | 2019-09-30T12:49:15Z | |
dc.date.available | 2019-09-30T12:49:15Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Bell, C. L., Rantanen, T., Chen, R., Davis, J., Petrovitch, H., Ross, G. W., & Masaki, K. (2014). Prestroke Weight Loss Is Associated With Poststroke Mortality Among Men in the Honolulu-Asia Aging Study. <i>Archives of Physical Medicine and Rehabilitation</i>, <i>95</i>(3), 472-479. <a href="https://doi.org/10.1016/j.apmr.2013.09.019" target="_blank">https://doi.org/10.1016/j.apmr.2013.09.019</a> | |
dc.identifier.other | CONVID_23759024 | |
dc.identifier.other | TUTKAID_62347 | |
dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/65686 | |
dc.description.abstract | Objective
To examine baseline prestroke weight loss and poststroke mortality among men.
Design
Longitudinal study of late-life prestroke body mass index (BMI), weight loss, and BMI change (midlife to late life) with up to 8-year incident stroke and mortality follow-up.
Setting
Community-based aging study data.
Participants
Japanese-American men (N=3581; age range, 71–93y) who were stroke free at baseline.
Interventions
Not applicable.
Main Outcome Measure
Poststroke mortality: 30 days poststroke, analyzed with stepwise multivariable logistic regression; and long-term poststroke (up to 8y), analyzed with stepwise multivariable Cox regression.
Results
Weight loss (4.5kg decrements) was associated with increased 30-day poststroke mortality (adjusted odds ratio=1.48; 95% confidence interval [CI], 1.14–1.92), long-term mortality after incident stroke (all types, n=225; adjusted hazards ratio (aHR)=1.25; 95% CI, 1.09–1.44), and long-term mortality after incident thromboembolic stroke (n=153; aHR=1.19; 95% CI, 1.01 to 1.40). Men with overweight/obese late-life BMI (≥25kg/m2, compared with healthy/underweight BMI) had increased long-term mortality after incident hemorrhagic stroke (n=54; aHR=2.27; 95% CI, 1.07–4.82). Neither desirable nor excessive BMI reductions (vs no change/increased BMI) were associated with poststroke mortality. In the overall sample (N=3581), nutrition factors associated with increased long-term mortality included the following: (1) weight loss (10lb decrements; aHR=1.15; 95% CI, 1.09–1.21), (2) underweight BMI (vs healthy BMI; aHR=1.76; 95% CI, 1.40–2.20), and (3) both desirable and excessive BMI reductions (vs no change or gain, separate model from weight loss and BMI; aHR range, 1.36–1.97; P<.001).
Conclusions
Although obesity is a risk factor for stroke incidence, prestroke weight loss was associated with increased poststroke (all types and thromboembolic) mortality. Overweight/obese late-life BMI was associated with increased posthemorrhagic stroke mortality. Desirable and excessive BMI reductions were not associated with poststroke mortality. Weight loss, underweight late-life BMI, and any BMI reduction were all associated with increased long-term mortality in the overall sample. | fi |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | |
dc.publisher | W.B.Saunders Co.; American Congress of Rehabilitation Medicine | |
dc.relation.ispartofseries | Archives of Physical Medicine and Rehabilitation | |
dc.rights | In Copyright | |
dc.subject.other | aged | |
dc.subject.other | mortality | |
dc.subject.other | stroke | |
dc.title | Prestroke Weight Loss Is Associated With Poststroke Mortality Among Men in the Honolulu-Asia Aging Study | |
dc.type | article | |
dc.identifier.urn | URN:NBN:fi:jyu-201909094064 | |
dc.contributor.laitos | Terveystieteiden laitos | fi |
dc.contributor.laitos | Department of Health Sciences | en |
dc.contributor.oppiaine | Gerontologia ja kansanterveys | fi |
dc.contributor.oppiaine | Gerontologian tutkimuskeskus | fi |
dc.contributor.oppiaine | Hyvinvoinnin tutkimuksen yhteisö | fi |
dc.contributor.oppiaine | Gerontology and Public Health | en |
dc.contributor.oppiaine | Gerontology Research Center | en |
dc.contributor.oppiaine | School of Wellbeing | en |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
dc.date.updated | 2019-09-09T12:15:18Z | |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
dc.description.reviewstatus | peerReviewed | |
dc.format.pagerange | 472-479 | |
dc.relation.issn | 0003-9993 | |
dc.relation.numberinseries | 3 | |
dc.relation.volume | 95 | |
dc.type.version | acceptedVersion | |
dc.rights.copyright | © 2014 by the American Congress of Rehabilitation Medicine | |
dc.rights.accesslevel | openAccess | fi |
dc.subject.yso | painoindeksi | |
dc.subject.yso | miehet | |
dc.subject.yso | kuntoutus | |
dc.subject.yso | laihdutus | |
dc.format.content | fulltext | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p21142 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p8173 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p3320 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p825 | |
dc.rights.url | http://rightsstatements.org/page/InC/1.0/?language=en | |
dc.relation.doi | 10.1016/j.apmr.2013.09.019 | |
dc.type.okm | A1 | |