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dc.contributor.authorSedliak, Milan
dc.contributor.authorZeman, Michal
dc.contributor.authorBuzgó, Gabriel
dc.contributor.authorCvecka, Jan
dc.contributor.authorHamar, Dusan
dc.contributor.authorLaczo, Eugen
dc.contributor.authorOkuliarova, Monika
dc.contributor.authorVanderka, Marian
dc.contributor.authorKampmiller, Tomas
dc.contributor.authorHäkkinen, Keijo
dc.contributor.authorAhtiainen, Juha
dc.contributor.authorHulmi, Juha
dc.contributor.authorNilsen, Tormod S.
dc.contributor.authorWiig, Håvard
dc.contributor.authorRaastad, Truls
dc.date.accessioned2019-06-13T07:40:56Z
dc.date.available2019-06-13T07:40:56Z
dc.date.issued2018
dc.identifier.citationSedliak, M., Zeman, M., Buzgó, G., Cvecka, J., Hamar, D., Laczo, E., Okuliarova, M., Vanderka, M., Kampmiller, T., Häkkinen, K., Ahtiainen, J., Hulmi, J., Nilsen, T. S., Wiig, H., & Raastad, T. (2018). Morphological, molecular and hormonal adaptations to early morning versus afternoon resistance training. <i>Chronobiology International</i>, <i>35</i>(4), 450-464. <a href="https://doi.org/10.1080/07420528.2017.1411360" target="_blank">https://doi.org/10.1080/07420528.2017.1411360</a>
dc.identifier.otherCONVID_27808072
dc.identifier.otherTUTKAID_76307
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/64588
dc.description.abstractIt has been clearly established that maximal force and power is lower in the morning compared to noon or afternoon hours. This morning neuromuscular deficit can be diminished by regularly training in the morning hours. However, there is limited and contradictory information upon hypertrophic adaptations to time-of-day-specific resistance training. Moreover, no cellular or molecular mechanisms related to muscle hypertrophy adaptation have been studied with this respect. Therefore, the present study examined effects of the time-of-day-specific resistance training on muscle hypertrophy, phosphorylation of selected proteins, hormonal concentrations and neuromuscular performance. Twenty five previously untrained males were randomly divided into a morning group (n = 11, age 23 ± 2 yrs), afternoon group (n = 7, 24 ± 4 yrs) and control group (n = 7, 24 ± 3 yrs). Both the morning and afternoon group underwent hypertrophy-type of resistance training with 22 training sessions over an 11-week period performed between 07:30–08:30 h and 16:00–17:00 h, respectively. Isometric MVC was tested before and immediately after an acute loading exclusively during their training times before and after the training period. Before acute loadings, resting blood samples were drawn and analysed for plasma testosterone and cortisol. At each testing occasion, muscle biopsies from m. vastus lateralis were obtained before and 60 min after the acute loading. Muscle specimens were analysed for muscle fibre cross-sectional areas (CSA) and for phosphorylated p70S6K, rpS6, p38MAPK, Erk1/2, and eEF2. In addition, the right quadriceps femoris was scanned with MRI before and after the training period. The control group underwent the same testing, except for MRI, between 11:00 h and 13:00 h but did not train. Voluntary muscle strength increased significantly in both the morning and afternoon training group by 16.9% and 15.2 %, respectively. Also muscle hypertrophy occurred by 8.8% and 11.9% (MRI, p < 0.001) and at muscle fibre CSA level by 21% and 18% (p < 0.01) in the morning and afternoon group, respectively. No significant changes were found in controls within these parameters. Both pre- and post-training acute loadings induced a significant (p < 0.001) reduction in muscle strength in all groups, not affected by time of day or training. The post-loading phosphorylation of p70S6Thr421/Ser424 increased independent of the time of day in the pre-training condition, whereas it was significantly increased in the morning group only after the training period (p < 0.05). Phosphorylation of rpS6 and p38MAPK increased acutely both before and after training in a time-of-day independent manner (p < 0.05 at all occasions). Phosphorylation of p70S6Thr389, eEF2 and Erk1/2 did not change at any time point. No statistically significant correlations were found between changes in muscle fibre CSA, MRI and cell signalling data. Resting testosterone was not statistically different among groups at any time point. Resting cortisol declined significantly from pre- to post-training in all three groups (p < 0.05). In conclusion, similar levels of muscle strength and hypertrophy could be achieved regardless of time of the day in previously untrained men. However, at the level of skeletal muscle signalling, the extent of adaptation in some parameters may be time of day dependent.fi
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherTaylor & Francis
dc.relation.ispartofseriesChronobiology International
dc.rightsIn Copyright
dc.subject.otherresistance training
dc.subject.otherskeletal muscle
dc.subject.otherhypertrophy
dc.subject.othercell signalling
dc.subject.otherdiurnal
dc.titleMorphological, molecular and hormonal adaptations to early morning versus afternoon resistance training
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201906123161
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineLiikuntafysiologiafi
dc.contributor.oppiaineValmennus- ja testausoppifi
dc.contributor.oppiaineExercise Physiologyen
dc.contributor.oppiaineScience of Sport Coaching and Fitness Testingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2019-06-12T12:15:13Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange450-464
dc.relation.issn0742-0528
dc.relation.numberinseries4
dc.relation.volume35
dc.type.versionacceptedVersion
dc.rights.copyright© Taylor & Francis, 2018.
dc.rights.accesslevelopenAccessfi
dc.subject.ysolihakset
dc.subject.ysovoimaharjoittelu
dc.subject.ysovuorokausirytmi
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p2784
jyx.subject.urihttp://www.yso.fi/onto/yso/p16233
jyx.subject.urihttp://www.yso.fi/onto/yso/p16613
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.1080/07420528.2017.1411360
dc.type.okmA1


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