N-Heterocyclic Carbene Catalyzed Asymmetric Synthesis of Pentacyclic Spirooxindoles via [3+3] Annulations of Isatin-Derived Enals and Cyclic N-Sulfonyl Ketimines
Liu, Q., Chen, X., Li, S., Rissanen, K., & Enders, D. (2019). N-Heterocyclic Carbene Catalyzed Asymmetric Synthesis of Pentacyclic Spirooxindoles via [3+3] Annulations of Isatin-Derived Enals and Cyclic N-Sulfonyl Ketimines. Advanced Synthesis and Catalysis, 361(9), 1991-1994. https://doi.org/10.1002/adsc.201900065
Published in
Advanced Synthesis and CatalysisDate
2019Copyright
© 2019 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
A convenient enantioselective route to new
types of pentacyclic spirooxindoles via [3+3] annulation
reactions of isatin-derived enals and cyclic N-sulfonyl
ketimines, using N-heterocyclic carbene (NHC) catalysis
has been developed. The new protocol leads to
pentacyclic spirooxindoles bearing a quaternary spirostereocenter in good yields and good to high
enantiomeric ratios.
Publisher
Wiley - VCH Verlag GmbH & Co. KGaAISSN Search the Publication Forum
1615-4150Keywords
Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/28923897
Metadata
Show full item recordCollections
License
Except where otherwise noted, this item's license is described as In Copyright