An extensive pattern of atypical neural speech-sound discrimination in newborns at risk of dyslexia
Thiede, A., Virtala, P., Ala-Kurikka, I., Partanen, E., Huotilainen, M., Mikkola, K., Leppänen, P. H., & Kujala, T. (2019). An extensive pattern of atypical neural speech-sound discrimination in newborns at risk of dyslexia. Clinical Neurophysiology, 130(5), 634-646. https://doi.org/10.1016/j.clinph.2019.01.019
Published in
Clinical NeurophysiologyAuthors
Date
2019Copyright
© 2019 International Federation of Clinical Neurophysiology.
Objective: Identifying early signs of developmental dyslexia, associated with deficient speech-sound
processing, is paramount to establish early interventions. We aimed to find early speech-sound processing
deficiencies in dyslexia, expecting diminished and atypically lateralized event-related potentials (ERP) and
mismatch responses (MMR) in newborns at dyslexia risk.
Methods: ERPs were recorded to a pseudoword and its variants (vowel-duration, vowel-identity, and
syllable-frequency changes) from 88 newborns at high or no familial risk. The response significance was
tested, and group, laterality, and frontality effects were assessed with repeated-measures ANOVA.
Results: An early positive and right-lateralized ERP component was elicited by standard pseudowords in
both groups, the response amplitude not differing between groups. Early negative MMRs were absent in
the at-risk group, and MMRs to duration changes diminished compared to controls. MMRs to vowel
changes had significant laterality x group interactions resulting from right-lateralized MMRs in controls.
Conclusions: The MMRs of high-risk infants were absent or diminished, and morphologically atypical,
suggesting atypical neural speech-sound discrimination.
Significance: This atypical neural basis for speech discrimination may contribute to impaired language
development, potentially leading to future reading problems.
...
Publisher
Elsevier Ireland Ltd.ISSN Search the Publication Forum
1388-2457Keywords
Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/28915209
Metadata
Show full item recordCollections
License
Related items
Showing items with similar title or keywords.
-
Neural phoneme discrimination in variable speech in newborns : Associations with dyslexia risk and later language skills
Virtala, P.; Kujala, T.; Partanen, E.; Hämäläinen, J. A.; Winkler, I. (Elsevier BV, 2023)A crucial skill in infant language acquisition is learning of the native language phonemes. This requires the ability to group complex sounds into distinct auditory categories based on their shared features. Problems in ... -
Brain responses to speech sounds in infants and children with and without familial risk for dyslexia
Lohvansuu, Kaisa (University of Jyväskylä, 2015)Dyslexia, a specific reading disability, runs in families. Therefore, the risk for a child to become dyslexic increases multifold if reading difficulties occur in the family. One risk factor for dyslexia is a deficit in ... -
Newborn brain responses measuring feature and change detection and predicting later language development in children with and without familial risk for dyslexia
Guttorm, Tomi (Jyväskylän yliopisto, 2003)Lukemisen erityisvaikeuksia eli kehityksellistä dysleksiaa on noin 3-10 prosentilla suomalaisista koululaisista. Vaikeudet haittaavat eri tavoin heidän koulusuoriutumistaan ja vaikuttavat näin myös tulevaisuuden ... -
Enhancement of brain event-related potentials to speech sounds is associated with compensated reading skills in dyslexic children with familial risk for dyslexia
Lohvansuu, Kaisa; Hämäläinen, Jarmo; Tanskanen, Annika; Ervast, Leena; Heikkinen, Elisa; Lyytinen, Heikki; Leppänen, Paavo H.T. (Elsevier; International Organization of Psychophysiology, 2014)Specific reading disability, dyslexia, is a prevalent and heritable disorder impairing reading acquisition characterized by a phonological deficit. However, the underlying mechanism of how the impaired phonological processing ...