Mismatch brain response to speech sound changes in rats
Ahmed, M., Mällo, T., Leppänen, P. H., Hämäläinen, J., Äyräväinen, L., Ruusuvirta, T., & Astikainen, P. (2011). Mismatch brain response to speech sound changes in rats. Frontiers in Psychology, 2(283). https://doi.org/10.3389/fpsyg.2011.00283
Julkaistu sarjassa
Frontiers in PsychologyTekijät
Päivämäärä
2011Tekijänoikeudet
© 2011 The Authors
Understanding speech is based on neural representations of individual speech sounds. In
humans, such representations are capable of supporting an automatic and memory-based
mechanism for auditory change detection, as reflected by the mismatch negativity (MMN)
of event-related potentials. There are also findings of neural representations of speech
sounds in animals, but it is not known whether these representations can support the
change detection mechanism analogous to that underlying the MMN in humans. To this
end, we presented synthesized spoken syllables to urethane-anesthetized rats while local
field potentials were epidurally recorded above their primary auditory cortex. In an oddball
condition, a deviant stimulus /ga/ or /ba/ (probability 1:12 for each) was rarely and randomly
interspersed between frequently presented standard stimulus /da/ (probability 10:12). In
an equiprobable condition, 12 syllables, including /da/, /ga/, and /ba/, were presented in a
random order (probability 1:12 for each). We found evoked responses of higher amplitude
to the deviant /ba/, albeit not to /ga/, relative to the standard /da/ in the oddball condition.
Furthermore, the responses to /ba/ were higher in amplitude in the oddball condition than
in the equiprobable condition. The findings suggest that anesthetized rat’s brain can form
representations of human speech sounds, and that these representations can support the
memory-based change detection mechanism analogous to that underlying the MMN in
humans. Our findings show a striking parallel in speech processing between humans and
rodents and may thus pave the way for feasible animal models of memory-based change
detection.
...
Julkaisija
Frontiers Research FoundationISSN Hae Julkaisufoorumista
1664-1078
Alkuperäislähde
http://www.frontiersin.org/auditory_cognitive_neuroscience/10.3389/fpsyg.2011.00283/fullJulkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/20802939
Metadata
Näytä kaikki kuvailutiedotKokoelmat
Lisenssi
Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
-
An extensive pattern of atypical neural speech-sound discrimination in newborns at risk of dyslexia
Thiede, Anja; Virtala, Paula; Ala-Kurikka, Iina; Partanen, Eino; Huotilainen, Minna; Mikkola, Kaija; Leppänen, Paavo H.T.; Kujala, Teija (Elsevier Ireland Ltd., 2019)Objective: Identifying early signs of developmental dyslexia, associated with deficient speech-sound processing, is paramount to establish early interventions. We aimed to find early speech-sound processing deficiencies ... -
Brain Responses to Letters and Speech Sounds and Their Correlations with Cognitive Skills Related to Reading in Children
Xu, Weiyong; Kolozsvari, Orsolya; Monto, Simo; Hämäläinen, Jarmo (Frontiers Research Foundation, 2018)Letter-speech sound (LSS) integration is crucial for initial stages of reading acquisition. However, the relationship between cortical organization for supporting LSS integration, including unimodal and multimodal processes, ... -
Depression-related alterations in deviance detection ERPs in the auditory and somatosensory modality
Topal, Volkan; Louhisto, Kasper (2022)Automaattisilla sähköfysiologisilla aivovasteilla mitatut kuulo- ja tuntoärsykemuutokset ovat potentiaalisia työkaluja masennuksen hermostollisten merkkien tunnistamiseksi. Kyseiset vasteet ovat kuitenkin saaneet osakseen ... -
Electrophysiological evidence for change detection in sound frequency and duration in mice
Kyläheiko, Iiris (2017)Ihmisaivot ovat taipuvaiset havaitsemaan muutoksia kuuloympäristössään. Elektrofysiologisissa mittauksissa tämän automaattisen muutoksen havaitsemisen merkkinä voidaan käyttää poikkeavuusnegatiivisuutta (MMN), joka on ... -
Electrophysiological evidence of memory-based detection of auditory regularity violations in anesthetized mice
Kurkela, Jari; Lipponen, Arto; Kyläheiko, Iiris; Astikainen, Piia (Nature Publishing Group, 2018)In humans, automatic change detection is reflected by an electrical brain response called mismatch negativity (MMN). Mismatch response is also elicited in mice, but it is unclear to what extent it is functionally similar ...
Ellei toisin mainittu, julkisesti saatavilla olevia JYX-metatietoja (poislukien tiivistelmät) saa vapaasti uudelleenkäyttää CC0-lisenssillä.