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dc.contributor.authorGagnon, Sheila S.
dc.contributor.authorNindl, Bradley C.
dc.contributor.authorVaara, Jani
dc.contributor.authorSanttila, Matti
dc.contributor.authorHäkkinen, Keijo
dc.contributor.authorKyröläinen, Heikki
dc.date.accessioned2018-08-13T06:55:53Z
dc.date.available2018-08-13T06:55:53Z
dc.date.issued2018
dc.identifier.citationGagnon, S. S., Nindl, B. C., Vaara, J., Santtila, M., Häkkinen, K., & Kyröläinen, H. (2018). Basal Endogenous Steroid Hormones, Sex Hormone-Binding Globulin, Physical Fitness, and Health Risk Factors in Young Adult Men. <i>Frontiers in Physiology</i>, <i>9</i>, 1005. <a href="https://doi.org/10.3389/fphys.2018.01005" target="_blank">https://doi.org/10.3389/fphys.2018.01005</a>
dc.identifier.otherCONVID_28175324
dc.identifier.otherTUTKAID_78337
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/59195
dc.description.abstractPurpose: Few large-scale population-based studies have adequately examined the relationships between steroid hormones, health status and physical fitness. The purpose of the study was to describe the relationship of serum basal endogenous steroid hormones (testosterone, TES; empirical free testosterone, EFT; cortisol, COR) and sex hormone-binding globulin (SHBG) to body composition, cardiovascular risk factors, and physical fitness in young healthy men. Methods: Male reservists (25 ± 4 years, N = 846) participated in the study. Basal TES, EFT, COR, and SHBG were measured in morning fasted blood. Stepwise regression analyses were used to examine associations between individual hormones to four separate categories: (1) body composition; (2) cardiovascular risk factors; (3) relative, and (4) absolute physical fitness. Results: Higher TES, EFT, and SHBG were associated with lower waist circumference (TES: β = −0.239, p < 0.001; EFT: β = −0.385, p < 0.001), % body fat (TES: β = −0.163, p = 0.003), and body mass index (SHBG: β = −0.435, p < 0.001). Lower cardiovascular risk factors were associated with higher TES, EFT and SHBG concentrations, especially between SHBG and triglycerides (β = −0.277, p < 0.001) and HDL (β = 0.154, p < 0.001). Greater maximal relative aerobic capacity was concurrent with higher TES, EFT, and SHBG (β = 0.171, 0.113, 0.263, p < 0.001, =0.005, <0.001, respectively). Conclusion: Higher basal concentrations of TES, EFT, and SHBG were weakly associated with healthier body composition, fewer cardiovascular risk factors and greater relative aerobic capacity in healthy young men. It would be interesting to investigate whether these relationships are still evident after a few decades, and how different training modes (endurance, strength or their combination) positively affect physical fitness, body composition and their regulatory mechanisms over the decades.fi
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherFrontiers Research Foundation
dc.relation.ispartofseriesFrontiers in Physiology
dc.rightsCC BY 4.0
dc.subject.othersex hormone-binding globulin
dc.subject.othercortisol
dc.subject.otherwaist circumference
dc.subject.othercardiovascular health
dc.titleBasal Endogenous Steroid Hormones, Sex Hormone-Binding Globulin, Physical Fitness, and Health Risk Factors in Young Adult Men
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201807303648
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineLiikuntafysiologiafi
dc.contributor.oppiaineValmennus- ja testausoppifi
dc.contributor.oppiaineExercise Physiologyen
dc.contributor.oppiaineScience of Sport Coaching and Fitness Testingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2018-07-30T09:15:17Z
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1005
dc.relation.issn1664-042X
dc.relation.numberinseries0
dc.relation.volume9
dc.type.versionpublishedVersion
dc.rights.copyright© 2018 Gagnon, Nindl, Vaara, Santtila, Häkkinen and Kyröläinen.
dc.rights.accesslevelopenAccessfi
dc.subject.ysotestosteroni
dc.subject.ysosukupuolihormonit
dc.subject.ysohormonit
dc.subject.ysosteroidit
dc.subject.ysofyysinen aktiivisuus
dc.subject.ysoliikunta
dc.subject.ysoterveysriskit
dc.subject.ysoterveysvaikutukset
dc.subject.ysomiehet
dc.subject.ysoaerobinen suorituskyky
dc.subject.ysofyysinen kunto
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p23240
jyx.subject.urihttp://www.yso.fi/onto/yso/p10984
jyx.subject.urihttp://www.yso.fi/onto/yso/p2589
jyx.subject.urihttp://www.yso.fi/onto/yso/p10983
jyx.subject.urihttp://www.yso.fi/onto/yso/p23102
jyx.subject.urihttp://www.yso.fi/onto/yso/p916
jyx.subject.urihttp://www.yso.fi/onto/yso/p11098
jyx.subject.urihttp://www.yso.fi/onto/yso/p15449
jyx.subject.urihttp://www.yso.fi/onto/yso/p8173
jyx.subject.urihttp://www.yso.fi/onto/yso/p24946
jyx.subject.urihttp://www.yso.fi/onto/yso/p7384
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.3389/fphys.2018.01005


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