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dc.contributor.authorAnnala, Riia
dc.contributor.authorSuhonen, Aku
dc.contributor.authorLaakkonen, Heikki
dc.contributor.authorPermi, Perttu
dc.contributor.authorNissinen, Maija
dc.date.accessioned2017-12-04T05:53:53Z
dc.date.available2018-11-04T22:35:44Z
dc.date.issued2017
dc.identifier.citationAnnala, R., Suhonen, A., Laakkonen, H., Permi, P., & Nissinen, M. (2017). Structural Tuning and Conformational Stability of Aromatic Oligoamide Foldamers. <em>Chemistry: A European Journal</em>, 23 (65), 16671-16680. <a href="https://doi.org/10.1002/chem.201703985">doi:10.1002/chem.201703985</a>
dc.identifier.otherTUTKAID_75549
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/56093
dc.description.abstractA series of aromatic oligoamide foldamers with two or three pyridine-2,6-dicarboxamide units as their main folding motifs and varying aromatic building blocks as linkers have been synthetized to study the effects of the structural variation on the folding properties and conformational stability. Crystallographic studies showed that in the solid state the central linker unit either elongates the helices and more open S-shaped conformations, compresses the helices to more compact conformations or acts as a rigid spacer separating the pyridine-2,6-dicarboxamide units, which for their part add the predictability of the conformational properties. Multidimensional NMR studies showed that, even in solution, foldamers show conformational stability and folded conformations comparable to the solid state structures.
dc.language.isoeng
dc.publisherWiley-VCH
dc.relation.ispartofseriesChemistry: A European Journal
dc.subject.otheraromatic oligoamide foldamers
dc.subject.otherstructures
dc.titleStructural Tuning and Conformational Stability of Aromatic Oligoamide Foldamers
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201711224337
dc.contributor.laitosKemian laitosfi
dc.contributor.laitosDepartment of Chemistryen
dc.contributor.oppiaineOrgaaninen kemia
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2017-11-22T13:15:22Z
dc.type.coarjournal article
dc.description.reviewstatuspeerReviewed
dc.format.pagerange16671-16680
dc.relation.issn0947-6539
dc.relation.volume23
dc.type.versionacceptedVersion
dc.rights.copyright© 2017 Wiley-VCH Verlag GmbH & Co. This is a final draft version of an article whose final and definitive form has been published by Wiley. Published in this repository with the kind permission of the publisher.
dc.rights.accesslevelopenAccessfi
dc.relation.doi10.1002/chem.201703985


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