Brain Responses to Sound Intensity Changes Dissociate Depressed Participants and Healthy Controls
Ruohonen, E., & Astikainen, P. (2017). Brain Responses to Sound Intensity Changes Dissociate Depressed Participants and Healthy Controls. Biological Psychology, 127, 74-81. https://doi.org/10.1016/j.biopsycho.2017.05.008
Published in
Biological PsychologyDate
2017Copyright
© 2017 Elsevier B.V. This is a final draft version of an article whose final and definitive form has been published by Elsevier. Published in this repository with the kind permission of the publisher.
Depression is associated with bias in emotional information processing, but less is known about the processing of neutral sensory stimuli. Of particular interest is processing of sound intensity which is suggested to indicate central serotonergic function. We tested weather event-related brain potentials (ERPs) to occasional changes in sound intensity can dissociate first-episode depressed, recurrent depressed and healthy control participants. The first-episode depressed showed larger N1 amplitude to deviant sounds compared to recurrent depression group and control participants. In addition, both depression groups, but not the control group, showed larger N1 amplitude to deviant than standard sounds. Whether these manifestations of sensory over-excitability in depression are directly related to the serotonergic neurotransmission requires further research. The method based on ERPs to sound intensity change is fast and low-cost way to objectively measure brain activation and holds promise as a future diagnostic tool.
...
![showless](/themes/JYX2//images/showless.png)
![showmore](/themes/JYX2//images/showmore.png)
Publisher
Elsevier BVISSN Search the Publication Forum
0301-0511Publication in research information system
https://converis.jyu.fi/converis/portal/detail/Publication/26995433
Metadata
Show full item recordCollections
Related items
Showing items with similar title or keywords.
-
Dissociating dysphoric and healthy control participants in brain’s electrical responses to sound intensity changes
Virtanen, Juho (2018)Ääni-intensiteetin prosessointi aivoissa on usein yhdistetty keskushermoston serotoniinijärjestelmän toimintaan. Tämän serotoniinijärjestelmän toimintahäiriön on ehdotettu olevan yksi piilevä tekijä masennuksen psykopatologian ... -
Pre-attentive and attentive processing of facial expressions in depressed older aged adults
Hämäläinen, Jasmin; Valtonen, Riina (2017) -
Brain responses to sound intensity changes in aging and in depression
Kattainen, Saara; Taskila, Anna-Elisa (2018)Sekä ikääntymisen että masennuksen on osoitettu olevan yhteydessä heikentyneeseen serotoniinijärjestelmän toimintaan, mikä voi heijastua aivojen automaattisen kykyyn käsitellä äänten voimakkuuksia. Äänen voimakkuuden ... -
Pre-attentive brain responses to mood-congruent facial expressions are sensitive to changes in depressive symptoms
Alhainen, Veera (2016)Tutkimukset ovat osoittaneet masentuneiden tarkkaavuuden kiinnittyvän helpommin mielialan kanssa yhteneväisiin kasvonilmeisiin. Ei ole kuitenkaan vielä varmaa voidaanko vääristymä havaita jo tarkkaavaisuutta edeltävässä ... -
Event-related potentials in response to irony in depressed and healthy controls
Haimi, Elina; Pesonen, Janne (2017)Humor has a positive impact on psychological and physiological well-being, and it improves social interaction and relationships. Depression is associated with numerous impairments, including affective symptoms and cognitive ...