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dc.contributor.authorRuohonen, Elisa
dc.contributor.authorAstikainen, Piia
dc.date.accessioned2017-05-31T10:14:19Z
dc.date.available2018-05-10T21:45:06Z
dc.date.issued2017
dc.identifier.citationRuohonen, E., & Astikainen, P. (2017). Brain Responses to Sound Intensity Changes Dissociate Depressed Participants and Healthy Controls. <i>Biological Psychology</i>, <i>127</i>, 74-81. <a href="https://doi.org/10.1016/j.biopsycho.2017.05.008" target="_blank">https://doi.org/10.1016/j.biopsycho.2017.05.008</a>
dc.identifier.otherCONVID_26995433
dc.identifier.otherTUTKAID_73737
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/54211
dc.description.abstractDepression is associated with bias in emotional information processing, but less is known about the processing of neutral sensory stimuli. Of particular interest is processing of sound intensity which is suggested to indicate central serotonergic function. We tested weather event-related brain potentials (ERPs) to occasional changes in sound intensity can dissociate first-episode depressed, recurrent depressed and healthy control participants. The first-episode depressed showed larger N1 amplitude to deviant sounds compared to recurrent depression group and control participants. In addition, both depression groups, but not the control group, showed larger N1 amplitude to deviant than standard sounds. Whether these manifestations of sensory over-excitability in depression are directly related to the serotonergic neurotransmission requires further research. The method based on ERPs to sound intensity change is fast and low-cost way to objectively measure brain activation and holds promise as a future diagnostic tool.
dc.language.isoeng
dc.publisherElsevier BV
dc.relation.ispartofseriesBiological Psychology
dc.subject.otherpre-attentive processing
dc.subject.otherERP
dc.subject.otherMMN
dc.subject.otherN1
dc.titleBrain Responses to Sound Intensity Changes Dissociate Depressed Participants and Healthy Controls
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201705292532
dc.contributor.laitosPsykologian laitosfi
dc.contributor.laitosDepartment of Psychologyen
dc.contributor.oppiainePsykologiafi
dc.contributor.oppiainePsychologyen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2017-05-29T06:15:03Z
dc.type.coarjournal article
dc.description.reviewstatuspeerReviewed
dc.format.pagerange74-81
dc.relation.issn0301-0511
dc.relation.numberinseries0
dc.relation.volume127
dc.type.versionacceptedVersion
dc.rights.copyright© 2017 Elsevier B.V. This is a final draft version of an article whose final and definitive form has been published by Elsevier. Published in this repository with the kind permission of the publisher.
dc.rights.accesslevelopenAccessfi
dc.subject.ysomasennus
dc.subject.ysoäänenvoimakkuus
dc.subject.ysopsykologia
dc.subject.ysokuulohavainnot
jyx.subject.urihttp://www.yso.fi/onto/yso/p7995
jyx.subject.urihttp://www.yso.fi/onto/yso/p4627
jyx.subject.urihttp://www.yso.fi/onto/yso/p1632
jyx.subject.urihttp://www.yso.fi/onto/yso/p23127
dc.relation.doi10.1016/j.biopsycho.2017.05.008


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