Reduced muscle inactivity, sedentary time and cardio-metabolic benefits : effectiveness of a one-year family-based cluster randomized controlled trial
Published inStudies in sport, physical education and health
A driving hypothesis of the evolving field of sedentary behavior is that frequent muscle activity short-circuits detrimental physiological effects of sedentary time. However, the field relies mostly on observational health associations of proxy measures of muscle inactivity, like television viewing or lack of accelerometer-derived impacts. This study tested effectiveness of a family-based cluster-randomized controlled trial aimed at reducing and breaking up sedentary time at work and leisure time of families on muscle inactivity patterns, sedentary time and cardio-metabolic biomarkers. The intervention consisted of a lecture, face-to-face tailored counseling, two follow-up calls and five emails during the first six months, and six months follow-up without the intervention. Detailed muscle inactivity and activity patterns of sitting, standing, normal daily life and the short-term efficacy of the counseling were quantified by special shorts capable of measuring average rectified EMG signal. The long-term effectiveness of the intervention was studied in 133 sedentary parents by measuring accelerometer-derived sedentary time, anthropometrics and blooddrawn cardio-metabolic biomarkers to report if short-term changes in muscle inactivity patterns translate to long-term behavioral and physiological benefits. The main findings of this study were that while muscles were inactive 90% of sitting time and the average muscle activity amplitude was threefold higher in standing (1.6% of EMGMVC) than sitting (0.5% of EMGMVC), the inter-individual differences were tenfold. However, within two weeks of the counseling muscle inactivity time decreased by 37 min in intervention group compared to controls without affecting high intensity activities suggesting that sedentary-time targeted intervention can change specifically muscle inactivity patterns. At three months the intervention was successful in reducing accelerometer-derived sedentary leisure time by 27 min in the intervention group as compared to controls. At 12 months the control group’s sedentary leisure time tended to increase whereas that of the intervention group remained at the baseline level suggesting that acutely effective intervention methods may prevent unfavorable long-term changes. Between baseline and endline, significant intervention effects in weight, total lean mass, leg’s lean mass, apoA-1 and apoB/apoA-1 -ratio favored intervention group and remained independent of moderate-to-vigorous -intensity physical activity and energy intake. In conclusion, the family-based tailored counseling was effective in reducing muscle inactivity and sedentary leisure time acutely, and in preventing an increase in sedentary leisure time during one year without reducing work or weekend sedentary time. This resulted also in some modest positive changes in anthropometrics and apolipoproteins independent of moderate-to-vigorous physical activity and energy intake. Reducing muscle inactivity produces causal health benefits and may bear public health potential. ...
PublisherUniversity of Jyväskylä
kardio-metaboliset markkerit muscle inactivity EMG textile electrodes sedentary behavior cluster-randomized controlled trial tailored counseling cardio-metabolic biomarkers istuminen lihakset passiivisuus elektromyografia liikkumattomuus terveyshaitat liikuntaneuvonta perhe hyötyliikunta kehonkoostumus fyysinen aktiivisuus edistäminen liikuntafysiologia
MetadataShow full item record
- Väitöskirjat 
Showing items with similar title or keywords.
Accelerometer-assessed sedentary work, leisure time and cardio-metabolic biomarkers during one year : Effectiveness of a cluster randomized controlled trial in parents with a sedentary occupation and young children Pesola, Arto; Laukkanen, Arto; Heikkinen, Risto; Sipilä, Sarianna; Sääkslahti, Arja; Finni Juutinen, Taija (Public Library of Science, 2017)Background It is unknown whether reducing sedentary time at work and during leisure time is possible and effective during one year. Methods Office workers with young children were recruited for this one-year ...
Effects of a sedentary behavior reduction intervention on common cardiometabolic risk factors in metabolic syndrome patients : a three-month randomized controlled trial Garthwaite, Taru (2020)Sedentary behavior is associated with metabolic disorders, cardiovascular disease, type 2 diabetes, and premature mortality. However, evidence regarding the health effects of sedentary behavior relies mainly on findings ...
Towards early risk biomarkers : serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood Ojanen, Xiaowei; Cheng, Runtan; Törmäkangas, Timo; Rappaport, Noa; Wilmanski, Tomasz; Wu, Na; Fung, Erik; Nedelec, Rozenn; Sebert, Sylvain; Vlachopoulos, Dimitris; Yan, Wei; Price, Nathan D.; Cheng, Sulin; Wiklund, Petri (Elsevier, 2021)Background Cardiovascular diseases may originate in childhood. Biomarkers identifying individuals with increased risk for disease are needed to support early detection and to optimise prevention strategies. Methods In ...
Body composition and molecular reflections of obesity-related cardio-metabolic disorders : a cross-sectional and longitudinal study in women Wiklund, Petri (University of Jyväskylä, 2016)
Physical activity and motor competence in 4-8-year old children : results of a family-based cluster-randomized controlled physical activity trial Laukkanen, Arto (University of Jyväskylä, 2016)This thesis addresses the following research questions: 1) what are the intensities of physical activities that are typically considered to develop motor competence in children, 2) how is accelerometer-derived physical ...