Delineating Margins of Lentigo Maligna Using a Hyperspectral Imaging System
Neittaanmäki-Perttu, N., Grönroos, M., Jeskanen, L., Pölönen, I., Ranki, A., Saksela, O., & Snellman, E. (2015). Delineating Margins of Lentigo Maligna Using a Hyperspectral Imaging System. Acta Dermato-Venereologica, 95(5), 549-552. https://doi.org/10.2340/00015555-2010
Julkaistu sarjassa
Acta Dermato-VenereologicaTekijät
Päivämäärä
2015Tekijänoikeudet
© 2015 The Authors. Published by the Society for the Publication of Acta Dermato-Venereologica.
Lentigo maligna (LM) is an in situ form of melanoma
which can progress into invasive lentigo maligna melanoma
(LMM). Variations in the pigmentation and thus
visibility of the tumour make assessment of lesion borders
challenging. We tested hyperspectral imaging system
(HIS) in in vivo preoperative delineation of LM and
LMM margins. We compared lesion margins delineated
by HIS with those estimated clinically, and confirmed
histologically. A total of 14 LMs and 5 LMMs in 19 patients
were included. HIS analysis matched the histopathological
analysis in 18/19 (94.7%) cases while in 1/19
(5.3%) cases HIS showed lesion extension not confirmed
by histopathology (false positives). Compared to clinical
examination, HIS defined lesion borders more accurately
in 10/19 (52.6%) of cases (wider, n=7 or smaller,
n=3) while in 8/19 (42.1%) cases lesion borders were the
same as delineated clinically as confirmed histologically.
Thus, HIS is useful for the detection of subclinical LM/
LMM borders. Key words: lentigo maligna; lentigo maligna
melanoma; tumour margin assessment; hyperspectral
imaging.
...
Julkaisija
Society for the Publication of Acta Dermato - VenereologicaISSN Hae Julkaisufoorumista
0001-5555Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/24680529
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