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DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression
(Elsevier BV, 2019)
Background
DNA mismatch repair (MMR) defects are a major factor in colorectal tumorigenesis in Lynch syndrome (LS) and 15% of sporadic cases. Some adenomas from carriers of inherited MMR gene mutations have intact MMR ...
DNA methylation links prenatal smoking exposure to later life health outcomes in offspring
(Biomed Central, 2019)
Background: Maternal smoking during pregnancy is associated with adverse offspring health outcomes across their life course. We hypothesize that DNA methylation is a potential mediator of this relationship.
Methods: We ...
Do adolescents with long-term illnesses and disabilities have increased risks of sports related injuries?
(Springer, 2017)
Background: The aim of this study is to examine the rates of sports related injuries in adolescents based on the
severity of their long-term illnesses or disabilities (LTID). Few injury prevention strategies in sports and ...
Do adverse events after manual therapy for back and/or neck pain have an impact on the chance to recover? A cohort study
(BioMed Central Ltd., 2019)
Background: Manual therapy is a commonly used treatment for patients with back and neck pain. Studies have
shown that manual therapy-related adverse events are mainly short in duration and mild or moderate by their
intensity, ...
Do Associations Between Perceived Environmental and Individual Characteristics and Walking Limitations Depend on Lower Extremity Performance Level?
(Sage Publications, Inc., 2017)
Objective: The aim of this study was to analyze whether the associations between perceived environmental and individual characteristics and perceived walking limitations in older people differ between those with intact and ...
Do bone geometric properties of the proximal femoral diaphysis reflect loading history, muscle properties, or body dimensions?
(John Wiley & Sons, Inc., 2019)
Objectives The aim of this study was to investigate activity-induced effects from bone geometric properties of the proximal femur in athletic vs nonathletic healthy females by statistically controlling for variation in ...
Do Epigenetic Clocks Provide Explanations for Sex Differences in Life Span? : A Cross-Sectional Twin Study
(Oxford University Press (OUP), 2022)
Background
The sex gap in life expectancy has been narrowing in Finland over the past four to five decades; however, on average, women still live longer than men. Epigenetic clocks are markers for biological aging that ...
Do factors related to participation in physical activity change following restrictive bariatric surgery? : A qualitative study
(Elsevier BV, 2018)
Aims
To explore participants’ ability to participate in physical activity (PA), and barriers and facilitators to PA, at 12 months following restrictive bariatric surgery, and how these differed from participants’ pre-surgery ...
Do Fundamental Movement Skill Domains in Early Childhood Predict Engagement in Physical Activity of Varied Intensities Later at School Age? A 3-Year Longitudinal Study
(Human Kinetics Publishers, 2023)
This study was conducted to determine how total fundamental movement skill (FMS) score and, separately, locomotor skill (LMS), and object control skill scores in children 3–8 years old predicted their specific-intensity ...
Do mobility, cognitive functioning, and depressive symptoms mediate the association between social activity and mortality risk among older men and women?
(Springer, 2014)
Social activity and health correlate in old age, but less is known about what explains this association. The aim of this study was to investigate whether mobility, cognitive functioning, and depressive symptoms mediate the ...