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dc.contributor.authorWalker, Simon
dc.contributor.authorSahinaho, Ulla-Maria
dc.contributor.authorVekki, Sakari
dc.contributor.authorSulonen, Mari
dc.contributor.authorLaukkanen, Jari A.
dc.contributor.authorSipilä, Sarianna
dc.contributor.authorPeltonen, Heikki
dc.contributor.authorLaakkonen, Eija
dc.contributor.authorLehti, Maarit
dc.date.accessioned2024-03-04T11:01:30Z
dc.date.available2024-03-04T11:01:30Z
dc.date.issued2024
dc.identifier.citationWalker, S., Sahinaho, U.-M., Vekki, S., Sulonen, M., Laukkanen, J. A., Sipilä, S., Peltonen, H., Laakkonen, E., & Lehti, M. (2024). Two-week step-reduction has limited negative effects on physical function and metabolic health in older adults. <i>European Journal of Applied Physiology</i>, <i>Early online</i>. <a href="https://doi.org/10.1007/s00421-024-05426-1" target="_blank">https://doi.org/10.1007/s00421-024-05426-1</a>
dc.identifier.otherCONVID_207400572
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/93795
dc.description.abstractPurpose This study determined the effects of a 2-week step-reduction period followed by 4-week exercise rehabilitation on physical function, body composition, and metabolic health in 70–80-year-olds asymptomatic for injury/illness. Methods A parallel-group randomized controlled trial (ENDURE-study, NCT04997447) was used, where 66 older adults (79% female) were randomized to either intervention or control group. The intervention group reduced daily steps to < 2000, monitored by accelerometer, for two weeks (Period I) and then step-reduction requirement was removed with an additional exercise rehabilitation 4 times per week for 4 weeks (Period II). The control group continued their habitual physical activity throughout with no additional exercise intervention. Laboratory tests were performed at baseline, after Period I and Period II. The primary outcome measure was leg lean mass (LLM). Secondary outcomes included total lean and fat mass, blood glucose and insulin concentration, LDL cholesterol and HDL cholesterol concentration, maximal isometric leg press force (MVC), and chair rise and stair climb performance. Results LLM remained unchanged in both groups and no changes occurred in physical function nor body composition in the intervention group in Period I. HDL cholesterol concentration reduced after Period I (from 1.62 ± 0.37 to 1.55 ± 0.36 mmol·L−1, P = 0.017) and returned to baseline after Period II (1.66 ± 0.38 mmol·L−1) in the intervention group (Time × Group interaction: P = 0.065). MVC improved after Period II only (Time × Group interaction: P = 0.009, Δ% = 15%, P < 0.001). Conclusion Short-term step-reduction in healthy older adults may not be as detrimental to health or physical function as currently thought.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofseriesEuropean Journal of Applied Physiology
dc.rightsCC BY 4.0
dc.subject.otherphysical activity
dc.subject.otherinactivity
dc.subject.otherHDL
dc.subject.otherexercise
dc.subject.otherwalking economy
dc.subject.otherstrength
dc.titleTwo-week step-reduction has limited negative effects on physical function and metabolic health in older adults
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202403042261
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.relation.issn1439-6319
dc.relation.volumeEarly online
dc.type.versionpublishedVersion
dc.rights.copyright© The Author(s) 2024
dc.rights.accesslevelopenAccessfi
dc.subject.ysovoimakkuus
dc.subject.ysofyysinen aktiivisuus
dc.subject.ysoHDL-kolesteroli
dc.subject.ysojoutilaisuus
dc.subject.ysoharjoittelu
dc.subject.ysokävely
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p22159
jyx.subject.urihttp://www.yso.fi/onto/yso/p23102
jyx.subject.urihttp://www.yso.fi/onto/yso/p16832
jyx.subject.urihttp://www.yso.fi/onto/yso/p8123
jyx.subject.urihttp://www.yso.fi/onto/yso/p26412
jyx.subject.urihttp://www.yso.fi/onto/yso/p3706
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1007/s00421-024-05426-1
jyx.fundinginformationOpen Access funding provided by University of Jyväskylä (JYU). This work was supported by a grant to SW from the Finnish Cultural Foundation (#00211177).
dc.type.okmA1


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