Synthesis and characterization of a novel coordination compound based on 2, 6-dimethylpiperazine

Abstract

Here we show the synthesis and complete characterization, including single crystal X-ray structure determination, of the first compound containing the monoprotonated 2,6-dimethylpiperazinium cation: (C6H15N2)+. Compound [Co(NCS)4(C6H15N2)2] (1) crystallizes in the monoclinic P21/n space group and contains an octahedral Co(II) ion surrounded by four -NCS and two protonated 2,6-dimethylpiperazine ligands (C6H15N2)+. There are some N-H•••S intermolecular hydrogen bonds that generate a three-dimensional H-bonded network. Compound 1 has been characterized by single-crystal and powder X-Ray diffraction, infrared, UV-Vis and RMN spectroscopies, thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The magnetic properties in the temperature range indicate the presence of isolated high spin Co(II) ions with the expected spin-orbit coupling. The antibacterial activity of compound 1 shows a higher antibacterial activity than other related complexes due to the presence of the piperazine-derivative ligands.