dc.contributor.author | Dahlous, Kholood A. | |
dc.contributor.author | Soliman, Saied M. | |
dc.contributor.author | Haukka, Matti | |
dc.contributor.author | El-Faham, Ayman | |
dc.contributor.author | Massoud, Raghdaa A. | |
dc.date.accessioned | 2023-03-29T12:02:02Z | |
dc.date.available | 2023-03-29T12:02:02Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Dahlous, K. A., Soliman, S. M., Haukka, M., El-Faham, A., & Massoud, R. A. (2023). A New 1D Ni (II) Coordination Polymer of s-Triazine Type Ligand and Thiocyanate as Linker via Unexpected Hydrolysis of 2,4-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine. <i>Inorganics</i>, <i>11</i>(3), Article 135. <a href="https://doi.org/10.3390/inorganics11030135" target="_blank">https://doi.org/10.3390/inorganics11030135</a> | |
dc.identifier.other | CONVID_178490179 | |
dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/86189 | |
dc.description.abstract | A new 1D Ni(II) coordination polymer was synthesized by the reaction of NiSO4·6H2O with 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (BPT) and SCN− as a linker in an acidic medium by heating under reflux conditions. Unusually, the BPT ligand underwent acid-mediated hydrolysis by losing one of the pyrazolyl arms afforded the polymeric [Ni(MPT)(H2O)(SCN)2]n complex (MPT: 4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazin-2-ol. The Ni(II) center is coordinated with one MPT as a bidentate NN-chelate, one water molecule, and two thiocyanate groups in cis positions to one another. One of the thiocyanate groups acts as a bridging ligand between metal centers, leading to a one-dimensional polymeric structure that extends along the c-direction. The other thiocyanate group is terminally N-coordinated. The [Ni(MPT)(H2O)(SCN)2]n complex has been screened in vitro against two pathogenic fungal strains: A. fumigatus, C. albican, and four pathogenic bacterial strains: S. aureus, B. subtilis as gram-positive bacteria, E. coli, P. vulgaris as gram-negative bacteria. The results showed that the complex has the potential to be used as both an antibacterial and an antifungal agent. Also, the [Ni(MPT)(H2O)(SCN)2]n complex showed cytotoxic activities against hepatocellular (HepG-2) and lung (A-549) cell lines, with IC50 values of 132.67 ± 5.14 and 146.97 ± 7.34 μM, respectively. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | |
dc.publisher | MDPI AG | |
dc.relation.ispartofseries | Inorganics | |
dc.rights | CC BY 4.0 | |
dc.subject.other | nickel (II) | |
dc.subject.other | s-triazine | |
dc.subject.other | antimicrobial | |
dc.subject.other | cytotoxicity | |
dc.subject.other | liver and lung carcinomas | |
dc.title | A New 1D Ni (II) Coordination Polymer of s-Triazine Type Ligand and Thiocyanate as Linker via Unexpected Hydrolysis of 2,4-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine | |
dc.type | research article | |
dc.identifier.urn | URN:NBN:fi:jyu-202303292329 | |
dc.contributor.laitos | Kemian laitos | fi |
dc.contributor.laitos | Department of Chemistry | en |
dc.contributor.oppiaine | Epäorgaaninen kemia | fi |
dc.contributor.oppiaine | Epäorgaaninen ja analyyttinen kemia | fi |
dc.contributor.oppiaine | Inorganic Chemistry | en |
dc.contributor.oppiaine | Inorganic and Analytical Chemistry | en |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
dc.description.reviewstatus | peerReviewed | |
dc.relation.issn | 2304-6740 | |
dc.relation.numberinseries | 3 | |
dc.relation.volume | 11 | |
dc.type.version | publishedVersion | |
dc.rights.copyright | © 2023 by the authors | |
dc.rights.accesslevel | openAccess | fi |
dc.type.publication | article | |
dc.subject.yso | maksa | |
dc.subject.yso | antimikrobiset yhdisteet | |
dc.subject.yso | karsinoomat | |
dc.subject.yso | nikkeli | |
dc.subject.yso | keuhkot | |
dc.format.content | fulltext | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p11264 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p21949 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p28373 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p19926 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p3185 | |
dc.rights.url | https://creativecommons.org/licenses/by/4.0/ | |
dc.relation.doi | 10.3390/inorganics11030135 | |
jyx.fundinginformation | This research received no external funding. | |
dc.type.okm | A1 | |