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Does Arsenic Contamination Affect DNA Methylation Patterns in a Wild Bird Population? : An Experimental Approach
Laine, Veronika N.; Verschuuren, Mark; van Oers, Kees; Espín, Silvia; Sánchez-Virosta, Pablo; Eeva, Tapio; Ruuskanen, Suvi (American Chemical Society (ACS), 2021)Pollutants, such as toxic metals, negatively influence organismal health and performance, even leading to population collapses. Studies in model organisms have shown that epigenetic marks, such as DNA methylation, can be ... -
From maternal glucocorticoid and thyroid hormones to epigenetic regulation of offspring gene expression : An experimental study in a wild bird species
Hukkanen, Mikaela; Hsu, Bin‐Yan; Cossin‐Sevrin, Nina; Crombecque, Mélanie; Delaunay, Axelle; Hollmen, Lotta; Kaukonen, Riina; Konki, Mikko; Lund, Riikka; Marciau, Coline; Stier, Antoine; Ruuskanen, Suvi (Wiley, 2023)Offspring phenotype at birth is determined by its genotype and the prenatal environment including exposure to maternal hormones. Variation in both maternal glucocorticoids and thyroid hormones can affect offspring phenotype, ... -
DNA Methylation and Potential for Epigenetic Regulation in Pygospio elegans
Kesäniemi, Jenni; Heikkinen, Liisa; Knott, Emily (Public Library of Science, 2016)Transitions in developmental mode are common evolutionarily, but how and why they occur is not understood. Developmental mode describes larval phenotypes, including morphology, ecology and behavior of larvae, which typically ... -
An ecologist’s guide for studying DNA methylation variation in wild vertebrates
Laine, Veronika N.; Sepers, Bernice; Lindner, Melanie; Gawehns, Fleur; Ruuskanen, Suvi; Oers, Kees (Wiley-Blackwell, 2023)The field of molecular biology is advancing fast with new powerful technologies, sequencing methods and analysis software being developed constantly. Commonly used tools originally developed for research on humans and model ... -
Leisure-Time and Occupational Physical Activity Associates Differently with Epigenetic Aging
Kankaanpää, Anna; Tolvanen, Asko; Bollepalli, Sailalitha; Leskinen, Tuija; Kujala, Urho M.; Kaprio, Jaakko; Ollikainen, Miina; Sillanpää, Elina (Lippincott Williams & Wilkins, 2021)Purpose: Greater leisure-time physical activity (LTPA) associates with healthier lives, but knowledge regarding occupational physical activity (OPA) is more inconsistent. DNA methylation (DNAm) patterns capture age-related ...