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dc.contributor.authorHautasaari, Pekka
dc.contributor.authorSaloranta, Harri
dc.contributor.authorSavić, Andrej M.
dc.contributor.authorKorniloff, Katariina
dc.contributor.authorKujala, Urho
dc.contributor.authorTarkka, Ina
dc.date.accessioned2021-01-20T11:59:33Z
dc.date.available2021-01-20T11:59:33Z
dc.date.issued2020
dc.identifier.citationHautasaari, P., Saloranta, H., Savić, A. M., Korniloff, K., Kujala, U., & Tarkka, I. (2020). Bilateral activations in operculo-insular area show temporal dissociation after peripheral electrical stimulation in healthy adults. <i>European Journal of Neuroscience</i>, <i>52</i>(12), 4604-4612. <a href="https://doi.org/10.1111/ejn.13946" target="_blank">https://doi.org/10.1111/ejn.13946</a>
dc.identifier.otherCONVID_28052576
dc.identifier.otherTUTKAID_77638
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/73701
dc.description.abstractInterhemispheric transfer is necessary for sensory integration and coordination of body sides. We studied how somatosensory input from one body side may reach both body sides. First, we investigated with 17 healthy adults in which uni‐ and bilateral brain areas were involved in consecutive stages of automatic sensory processing of non‐nociceptive peripheral stimulation. Somatosensory evoked fields (SEFs) to electrical stimulation were recorded with 306‐channel magnetoencephalography in two conditions. First, SEFs were registered following sensory radial nerve (RN) stimulation to dorsal surface of the right hand and second, following median nerve (MN) stimulation at the right wrist. Cortical activations were located in contralateral postcentral gyrus after MN and RN stimulations and in bilateral operculo‐insular area after RN stimulation. First component occurred earlier after MN than RN stimulation. Middle latency components had similar latencies with stronger activation in contralateral postcentral gyrus after MN than RN stimulation. Interestingly, long latency components located in bilateral operculo‐insular area after RN stimulation showed latency difference between hemispheres, i.e. activation peaked earlier in contralateral than in ipsilateral side. Additional experiments comparing novel intracutaneous nociceptive, RN and MN electrical stimuli confirmed bilateral long latency activation elicited by each stimulus type and highlighted latency differences between hemispheres. Variations in activation of bilateral operculo‐insular areas may corroborate their role in pain network and in multisensory integration. Our findings imply that these areas present a relay station in multisensory stimulus detection.fi
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherWiley-Blackwell Publishing Ltd.
dc.relation.ispartofseriesEuropean Journal of Neuroscience
dc.rightsIn Copyright
dc.subject.othermagnetoencephalography
dc.subject.othersensory cortex
dc.subject.othernociception
dc.subject.othermedian nerve
dc.subject.otherradial nerve
dc.titleBilateral activations in operculo-insular area show temporal dissociation after peripheral electrical stimulation in healthy adults
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202101051016
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineFysioterapiafi
dc.contributor.oppiaineLiikuntalääketiedefi
dc.contributor.oppiaineMonitieteinen aivotutkimuskeskusfi
dc.contributor.oppiaineHyvinvoinnin tutkimuksen yhteisöfi
dc.contributor.oppiainePhysiotherapyen
dc.contributor.oppiaineSports and Exercise Medicineen
dc.contributor.oppiaineCentre for Interdisciplinary Brain Researchen
dc.contributor.oppiaineSchool of Wellbeingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2021-01-05T13:15:05Z
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange4604-4612
dc.relation.issn0953-816X
dc.relation.numberinseries12
dc.relation.volume52
dc.type.versionacceptedVersion
dc.rights.copyright© 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd
dc.rights.accesslevelopenAccessfi
dc.subject.ysohermosto
dc.subject.ysoaivokuori
dc.subject.ysotuntoaisti
dc.subject.ysoMEG
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p3750
jyx.subject.urihttp://www.yso.fi/onto/yso/p7039
jyx.subject.urihttp://www.yso.fi/onto/yso/p3330
jyx.subject.urihttp://www.yso.fi/onto/yso/p3329
dc.rights.urlhttp://rightsstatements.org/page/InC/1.0/?language=en
dc.relation.doi10.1111/ejn.13946
jyx.fundinginformationThe study was funded by Juho Vainio Foundation, Helsinki, Finland grant (201410296) and Ministry of Education and Culture, Helsinki, Finland (OKM/56/626/2013).
dc.type.okmA1


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