How can dementia and disability be prevented in older adults : Where are we today and where are we going?
Lisko, I., Kulmala, J., Annetorp, M., Ngandu, T., Mangialasche, F., & Kivipelto, M. (2021). How can dementia and disability be prevented in older adults : Where are we today and where are we going?. Journal of Internal Medicine, 289(6), 807-830. https://doi.org/10.1111/joim.13227
Published inJournal of Internal Medicine
DisciplineGerontologia ja kansanterveysGerontologian tutkimuskeskusGerontology and Public HealthGerontology Research Center
© 2020 The Authors. Journal of Internal Medicine published by John Wiley & Sons Ltd on behalf of Association for Publication of The Journal of Internal Medicine.
Ageing of the population, together with population growth, has brought along an ample increase in the number of older individuals living with dementia and disabilities. Dementia is the main cause of disability in old age and promoting healthy brain ageing is considered as a key element in diminishing the burden of age‐related disabilities. The World Health Organization recently launched the first risk reduction guidelines for cognitive impairment and dementia. According to recent estimates approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors: low education; midlife hypertension and obesity; diabetes, smoking, excessive alcohol use, physical inactivity, depression, low social contact, hearing loss, traumatic brain injury and air pollution indicating clear prevention potential. Dementia and physical disability are closely linked with shared risk factors and possible shared underlying mechanisms supporting the possibility of integrated preventive interventions. FINGER trial was the first large randomized controlled trial indicting that multidomain lifestyle‐based intervention can prevent cognitive and functional decline among at risk older adults from the general population. Within the World‐Wide FINGERS network, the multidomain FINGER concept is now tested and adapted worldwide proving evidence and tools for effective and easily implementable preventive strategies. Close collaboration between researchers, policy makers, and health care practitioners, involvement of older adults and utilization of new technologies to support self‐management is needed to facilitate implementation of the research findings. In this scoping review, we present the current scientific evidence in the field of dementia and disability prevention and discuss future directions in the field. ...
ISSN Search the Publication Forum0954-6820
Publication in research information system
MetadataShow full item record
- Liikuntatieteiden tiedekunta 
Related funder(s)Academy of Finland
Funding program(s)Postdoctoral Researcher, AoF
Additional information about fundingAcknowledgments This work was financially supported by Juho Vainio Foundation, Finnish Cultural Foundation, Yrjö Jahnsson Foundation, Alzheimer’s Research and Prevention Foundation, Jalmari and Rauha Ahokas Foundation; Academy of Finland (grant numbers 334419 and 317465); EURO-FINGERS, an EU Joint Programme - Neurodegenerative Disease Research (JPND) project (supported through the following funding organisations under the aegis of JPND - www.jpnd.eu Finland: Academy of Finland (grant number 334804); Sweden: Swedish Research Council (grant number 2019-02226); Alzheimerfonden Sweden, Knut and Alice Wallenberg Foundation; Center for Innovative Medicine (CIMED) at Karolinska Institutet, Sweden, Region Stockholm (ALF grant), Sweden; Stiftelsen Stockholms sjukhem, Konung Gustaf V:s och Drottning Victorias Frimurarstiftelse ...
Showing items with similar title or keywords.
Long-term strength and balance training prevents mobility decline among community-dwelling people aged 75 and older Aartolahti, Eeva (University of Jyväskylä, 2016)High functional capacity of muscle strength and balance in older persons promotes independent mobility and prevents functional decline below the disability threshold. This dissertation explored the effects of strength ...
Psychological resilience and active aging among older people with mobility limitations Siltanen, Sini; Tourunen, Anu; Saajanaho, Milla; Palmberg, Lotta; Portegijs, Erja; Rantanen, Taina (Springer, 2021)Active aging refers to striving for well-being through preferred activity and may be restricted with declining mobility. We investigated whether psychological resilience, i.e., the ability to tolerate hardship, can aid ...
Maatilapäivätoiminnan merkitys ikääntyneille Rantanen, Virpi (2018)Ikääntyneiden ihmisten kotona asumista korostava vanhuspolitiikka painottaa ennaltaehkäisevien toimintamallien kehittämistä. Euroopassa viime vuosina kasvussa olleen green care –maatilapäivätoiminnan on kansainvälisissä ...
Mobility limitation, balance impairment and musculoskeletal pain among people aged ≥75 years : a study with a comprehensive geriatric intervention Lihavainen, Katri (University of Jyväskylä, 2012)
The Healthy Nordic Diet and Mediterranean Diet and Incidence of Disability 10 Years Later in Home-Dwelling Old Adults Perälä, Mia-Maria; von Bonsdorff, Mikaela; Männistö, Satu; K.Salonen, Minna; Simonen, Mika; Pohjolainen, Pertti; Kajantie, Eero; Rantanen, Taina; Eriksson, Johan G. (Elsevier Inc., 2019)Background/Objective: Diet has a major impact on a person's health. However, limited information exists on the long-term role of the whole diet on disability. We investigated the association of the healthy Nordic diet and ...